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The hype around ctDNA guiding an informed perioperative therapeutic strategy in early-stage non-small cell lung cancer.
Discov Oncol
January 2025
Medical Oncology Unit, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
Non-small cell lung cancer (NSCLC) remains a dire disease being the first cause of cancer death among both genders. Early-stage NSCLC often has better treatment outcomes despite it being a highly heterogeneous disease. So far, the neo-adjuvant chemotherapy strategies have led to a small benefit with an improvement of 5% in overall survival as an absolute benefit.
View Article and Find Full Text PDFA comparison of virtual reality and verbal imaginal exposure for childhood anxiety disorders.
J Anxiety Disord
January 2025
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.
Virtual reality is a promising tool for improving efficacy of exposure therapy for childhood anxiety disorders (CADs), particularly for exposures that are challenging to orchestrate in vivo. The present study compared virtual reality exposure (VRE) to verbal imaginal exposure (IE) on anxiety elicited, homework completion, and preparation for subsequent exposures. Forty-five youth with CADs completed both types of exposure in session (order randomly assigned), practiced one form of exposure as homework (randomly assigned), and returned a week later to repeat both exposures (in randomized order), provide user feedback, and complete a related in vivo exposure.
View Article and Find Full Text PDFBiogeochemical study of spent gunshot fate in the environment: Influence of aggressive bacterial strain.
Chemosphere
January 2025
University of Rzeszow, Institute of Food Technology and Nutrition, Zelwerowicza 4, 35-601, Rzeszow, Poland.
The hunting of waterfowl may contribute significantly to environmental contamination through the leaching of highly toxic elements (As, Pb, Sb) from spent gunshot deposited on hunting grounds. It is therefore clearly necessary to develop a biogeochemical protocol that might decipher the fate of spent gunshot in the environment. In that context, we present a study that follows the laboratory simulation approach and discusses the methodical pros and cons of the protocol.
View Article and Find Full Text PDFThe pros and cons of beta-blockers in sepsis: Where do we stand in 2024?
J Intensive Med
January 2025
Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Advancements in liver retraction techniques for laparoscopic gastrectomy.
World J Gastrointest Surg
January 2025
Department of Upper Gastrointestinal Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2GW, West Midlands, United Kingdom.
Traditionally, liver retraction for laparoscopic gastrectomy is done manual methods, such as the placement of retractors through the accessory ports and using a Nathanson retractor. However, these techniques often posed issues including extra abdominal incisions, risk of liver injury or ischaemia, and the potential for compromised visualization. Over the years, the development of innovative liver retraction techniques has significantly improved the safety and efficacy of laparoscopic gastrectomy and similar other hiatal procedures.
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