AI Article Synopsis
- Researchers monitored the expression of listeriolysin O, an important virulence factor in Listeria monocytogenes, using a specific transcriptional fusion.
- The phenolic compound arbutin was found to reduce the transcription of listeriolysin O.
- In contrast, salicin, a similar compound, did not affect the expression of listeriolysin O.
Article Abstract
Expression of the listeriolysin O, a key virulence factor for Listeria monocytogenes, was monitored using a hlyA-luxAB transcriptional fusion. The phenolic beta-D-glucoside, arbutin, was found to repress the expression of the listeriolysin O at the level of transcription. In contrast, the structurally similar beta-glucoside salicin did not prevent expression of listeriolysin.
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