It was shown with endothelium-containing and endothelium-denuded aorta segments that external gamma-irradiation of rats (6.0 Gy) results in intensification of vasodilatation reactions on beta-adrenoceptor stimulation by isoprenaline with maximum in 30th day of post-radiation period. This post-radiation alteration is not related with endothelium-derived relaxing factor.
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