Gliomas frequently occur in boxer dogs and are often located in the rhinencephalic allocortex. This brain region contains unusual glial cell nests (GCN). The presence of structural abnormalities in the GCN in the boxer dog might indicate that they are involved in the development of gliomas, which would explain the predisposition of this canine breed for glioma formation. Therefore, the brains of six brachycephalic (boxer dogs) and five dolichocephalic dogs were investigated morphometrically. The volumes of the whole brain, the allocortex, and the GCN were estimated following Cavalieri's principle. Unbiased estimates of the numerical density and total number of the two prevailing cell populations within the GCN were obtained using the optical disector method. There was no significant difference for the estimated parameters between brachycephalic and dolichocephalic dogs. The results of the present study did not show any evidence of boxer dog-specific features of the GCN, thus, failing to explain the striking glioma predisposition of boxer dogs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF00309341 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
CSF flow measurement in the mesencephalic aqueduct using 2D cine phase-contrast MRI in dogs with communicating internal hydrocephalus, ventriculomegaly, and physiologic ventricular spaces.
Front Vet Sci
November 2024
Department of Veterinary Clinical Sciences, Small Animal Clinic - Neurosurgery, Neuroradiology and Clinical Neurology, Justus-Liebig-University, Giessen, Germany.
Background: Brachycephalic dogs are overrepresented with ventricular enlargement. Cerebrospinal fluid (CSF) flow dynamics are not completely understood. MRI techniques have been used for the visualization of CSF dynamics including phase-contrast imaging.
View Article and Find Full Text PDFComputed tomographic characteristics of anatomical variations of external and internal jugular veins in dogs.
Vet Radiol Ultrasound
November 2024
Department of Veterinary Clinical Sciences, Louisiana State University, Baton Rouge, Louisiana, USA.
The external jugular vein (EJV) has been commonly used for clinical procedures in veterinary medicine, while the internal jugular vein (IJV) has been used mainly for research. Limited literature regarding anatomical variants in both EJV and IJV is available. The objectives of this descriptive retrospective study were to identify the number of dogs with variations of the jugular veins in canine patients undergoing CT of the head and neck and characterize these variations.
View Article and Find Full Text PDFSalivary cortisol measurements in brachycephalic dog breeds as part of a standardized stress test.
Front Vet Sci
July 2024
Veterinary Faculty, Clinic of Small Animal Surgery and Reproduction, Ludwig-Maximilians-Universität München, Munich, Germany.
Introduction: Brachycephalic obstructive airway syndrome (BOAS) is a common condition in brachycephalic dogs, with Pugs (PG) and French Bulldogs (FB) appearing to be particularly typically affected. Objective and easy-to-perform tests are necessary to detect the disease at an early stage and to exclude dogs affected by BOAS from breeding.
Methods: The present study investigated the extent to which vital signs and salivary cortisol concentrations can be used to distinguish between healthy and BOAS-affected dogs in a standardized fitness test.
Investigation of ocular surface parameters in dogs with different cephalic conformations using veterinary ocular surface analyzer (OSA-VET).
Vet Ophthalmol
July 2024
Institute of Veterinary Clinical Sciences, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
Article Synopsis
- The study investigated ocular surface parameters in 68 privately owned dogs with different head shapes, categorizing them as brachycephalic, mesocephalic, and dolichocephalic based on their craniofacial ratio (CFR).
- It found that brachycephalic dogs had significantly poorer tear film stability (measured by TBUT and NIBUT) and lipid layer thickness, while having a higher tear meniscus height compared to the other groups.
- The results suggest that brachycephalic dogs are at a higher risk for eye conditions like keratoconjunctivitis sicca due to their anatomical features, and the OSA-VET device is useful for diagnosing these ocular surface issues more accurately
Morphological and morphometric measurement of the temporomandibular joint of small and medium-weight dogs with different skull shapes.
Front Vet Sci
May 2024
Department of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Hannover, Germany.
Background: The recognition and diagnosis of canine temporomandibular joint (TMJ) disease can be a challenge, often leaving them undiagnosed. Although computed tomography (CT) has proved to be highly efficacious in detecting joint disease in the TMJ, morphometric and morphological studies of the normal TMJ have been scarce. Especially, skull type specific anatomical differences of the TMJ in dogs of different weights and skull morphologies have received limited attention.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!