Purpose: To determine the frequency with which stereotaxic core biopsy of the breast obviated diagnostic surgical biopsy and to estimate the savings in cost of diagnosis with this procedure.
Materials And Methods: Stereotaxic core biopsy of 182 nonpalpable, mammographically evident lesions was performed, and data from clinical follow-up were obtained. Savings in cost were assessed by using national Medicare reimbursement data and a relative value system based on national physician reviews (Relative Values for Physicians [RVP]).
Results: Stereotaxic core biopsy replaced a surgical procedure in 140 of 182 patients. The mean adjusted direct savings in cost per stereotaxic core biopsy were $893 (Medicare) or $1,491 (RVP). Use of stereotaxic core biopsy decreased the cost of diagnosis by 52% (RVP) or 55% (Medicare).
Conclusion: Stereotaxic core biopsy obviated surgical biopsy for most nonpalpable lesions sampled, resulting in a greater than 50% reduction in biopsy costs. If these results were generalizable to the national level, annual savings would approach $200 million.
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http://dx.doi.org/10.1148/radiology.195.3.7753986 | DOI Listing |
J Med Imaging Radiat Oncol
June 2024
Department of Medical Imaging, Royal Perth Hospital, Perth, Western Australia, Australia.
Introduction: Contrast-enhanced mammography (CEM) and MRI detect 'contrast-only' lesions (COLs) occult on standard breast imaging (ultrasound and conventional mammography). Until recently, MRI was the only reliable method of biopsy. This study presents the first Australian experience with CEM-guided biopsy (CEMBx) and the lessons learnt.
View Article and Find Full Text PDFAngiogenesis
August 2024
Department of Neurosurgery, Xuanwu Hospital, China International Neuroscience Institute, Capital Medical University, 45 Changchun St, Beijing, 100053, China.
Current treatments of brain arteriovenous malformation (BAVM) are associated with considerable risks and at times incomplete efficacy. Therefore, a clinically consistent animal model of BAVM is urgently needed to investigate its underlying biological mechanisms and develop innovative treatment strategies. Notably, existing mouse models have limited utility due to heterogenous and untypical phenotypes of AVM lesions.
View Article and Find Full Text PDFSeizure
April 2024
Neurosciences and Mental Health, Hospital for Sick Children, 686 Bay St, Toronto, Ontario, M5G 0A4, Canada; Institute of Biomedical Engineering, University of Toronto, 164 College St, Toronto, Ontario, M5S 3E2, Canada; Division of Neurosurgery, Hospital for Sick Children, 555 University Ave, Toronto, Ontario, M5G 1×8, Canada; Department of Surgery, University of Toronto, 149 College St, Toronto, Ontario, M5T 1P5, Canada. Electronic address:
Purpose: Stereoelectroencephalography (sEEG) is increasingly utilized for localization of seizure foci, functional mapping, and neurocognitive research due to its ability to target deep and difficult to reach anatomical locations and to study in vivo brain function with a high signal-to-noise ratio. The research potential of sEEG is constrained by the need for accurate localization of the implanted electrodes in a common template space for group analyses.
Methods: We present an algorithm to automate the grouping of sEEG electrodes by trajectories, labelled by target and insertion point.
J Clin Neurosci
May 2024
Department of Neurosurgery, Osaka Metropolitan University, Graduate School of Medicine, Osaka, Japan.
Background: Seizure onset pattern (SOP) represents an alteration of electroencephalography (EEG) morphology at the beginning of seizure activity in epilepsy. With stereotactic electroencephalography (SEEG), a method for intracranial EEG evaluation, many morphological SOP classifications have been reported without established consensus. These inconsistent classifications with ambiguous terminology present difficulties to communication among epileptologists.
View Article and Find Full Text PDFFront Neurosci
March 2024
Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology, NTNU, Trondheim, Norway.
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