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Feasibility and impact of sentinel lymph node biopsy in patients affected by ano-rectal melanoma.
Tech Coloproctol
January 2025
Department of Surgical Sciences, University of Turin, Turin, Italy.
Introduction: Anorectal melanoma (ARM) is rare and highly lethal neoplasm. It has a poorer prognosis compared with cutaneous ones. Sentinel lymph node biopsy (SLNB) has become the preferred method of nodal staging method for cutaneous melanoma.
View Article and Find Full Text PDFValidated approaches at mayo clinic for measuring gastric and colonic transit of solids and gastric accommodation.
Expert Rev Gastroenterol Hepatol
November 2024
Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.), Division of Gastroenterology and Hepatology; Division of Nuclear Medicine, Department of Radiology Mayo Clinic, Rochester, MN, USA.
Introduction: Advancements in scintigraphic gastrointestinal motility testing that were developed, validated, and replicated in clinical practice at Mayo Clinic have significantly enhanced our understanding and management of gastrointestinal motility disorders. Importantly, normative values in at least 100 healthy controls and estimated inter- and intra-individual coefficient of variation for all parameters have been published for these tests.
Areas Covered: This article reviews methodology, accuracy, reproducibility, and diagnostic cutoffs of scintigraphic techniques for measuring gastric emptying, gastric accommodation, and colonic transit, comparing methods from Mayo Clinic with those used elsewhere when appropriate.
Pre-symptomatic scintigraphic and genetic cascade screening in cardiac transthyretin amyloidosis.
Eur J Nucl Med Mol Imaging
November 2024
Jagiellonian University Medical College, Department of Cardiac and Vascular Diseases, Institute of Cardiology, St. John Paul II Hospital, Pradnicka 80, 31-202, Krakow, Poland.
Purpose: While early diagnosis is crucial, as new treatments can significantly slow the progression of the disease, there is growing evidence on the application of novel imaging techniques for detecting transthyretin amyloidosis (ATTR) in pre-symptomatic stages. This study aimed to evaluate the utility of pre-symptomatic scintigraphic imaging cascade screening for early detection of ATTR.
Methods: During the period from 2020 to 2024, we conducted a prospective study that enrolled 100 consecutive adults.
Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study.
Medicina (Kaunas)
October 2024
Faculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, Turkey.
Article Synopsis
- The study focuses on tendon injuries in complex wounds of the hand and lower extremities, exploring how different types of adipofascial tissue flaps affect healing and functional recovery.
- It compares vascularised versus nonvascularised adipofascial flaps using Wistar Albino rats, assessing healing through scintigraphic evaluations and histopathological analysis.
- Results indicate that vascularised flaps promote faster healing while pedicle-free flaps also aid tendon recovery without complications, providing insights for improving tendon repair techniques in reconstructive surgery.
Simultaneous segmentation and classification of Tc-DMSA renal scintigraphic images with a deep learning approach.
EJNMMI Rep
October 2024
School of Biomedical Engineering, ShanghaiTech University, Shanghai, China.
Background: Tc-DMSA scan plays an important role in assessing functional abnormalities in kidneys. As a promising network for deep learning (DL), Mask R-CNN has the capability of simultaneously segmenting and classifying objects in images. In this study, we tested the feasibility and accuracy of Mask R-CNN in diagnosing acute pyelonephritis (APN) and segmenting kidneys in Tc-DMSA scintigraphic images.
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