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Localised Hypersensitivity Reaction to Polysorbate 80 During Secukinumab Treatment: A Case of Injection-Site Contact Urticaria.
Contact Dermatitis
December 2024
Dermatology Department, Hospital del Mar Research Institute, Barcelona, Spain.
Enhancing docetaxel efficacy and reducing toxicity using biodegradable periodic mesoporous organosilica nanoparticles.
Heliyon
November 2024
Center for Innovative Materials and Architectures (INOMAR), Ho Chi Minh City, Viet Nam.
Taxanes, such as docetaxel (DTX), are pivotal in cancer therapy, showcasing remarkable efficacy against various cancers, like breast, lung, and ovarian malignancies. However, DTX's efficacy is hindered by poor target specificity and significant adverse effects. Formulations containing DTX often include polysorbate 80 and ethanol, exacerbating reactions like hypersensitivity and neurological disorders.
View Article and Find Full Text PDFCOVID-19 vaccines: anaphylaxis and anxiety : A case study from an allergy unit.
Wien Klin Wochenschr
November 2024
Department of Dermatology and Venereology, Medical University of Graz, Auenbruggerplatz 8, 8036, Graz, Austria.
Background: Vaccination against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) was one crucial element to overcome the coronavirus disease 2019 (COVID-19) pandemic. Even though anaphylaxis to vaccines is rare, 47 patients came to the Allergy Unit at the University Hospital Graz, Austria, reporting immediate anaphylactoid symptoms after administration of COVID-19 vaccines. In addition, 29 patients with known drug-induced anaphylaxis wanted to be tested for a possible sensitization against COVID-19 vaccines or excipients, such as polyethylene glycol (PEG) or polysorbate 80 (PS80) before the first COVID-19 vaccination.
View Article and Find Full Text PDFNeurological manifestations of immune origin after COVID-19 vaccination: retrospective case study.
Front Pharmacol
August 2024
Neurology Department and Stroke Center, Laboratory of Neurological and Cerebrovascular Sciences, Hospital La Paz Institute for Health Research Institute-IdiPAZ (La Paz University Hospital-Universidad Autónoma de Madrid), Madrid, Spain.
To know the frequency and characteristics of neurological manifestations of probable immune origin occurring after exposure to COVID-19 vaccination. In addition, to pre-study the usefulness of the Spanish pharmacovigilance system and lymphocyte transformation test in establishing causality. Retrospective case study, including patients admitted to the Neurology department from January 2021 to May 2022 with a probable neuroimmune disorder.
View Article and Find Full Text PDFAmiodarone-Induced Anaphylaxis.
J Pharm Pract
February 2025
Department of Biomedical Sciences, Rocky Vista University College of Osteopathic Medicine, Ivins, UT, USA.
Amiodarone-induced anaphylaxis is seldom reported. The mechanism of this anaphylaxis is unknown. A literature search was carried out with keywords "Amiodarone" and "Anaphylaxis" and "polysorbate 80" or "hypotension.
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