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Improving Septicemia Diagnostics: A Comparative Analysis of Direct and Post-Culture MALDI-TOF MS Methods for Bacterial Identification.
Tunis Med
December 2024
Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco.
Introduction: Bloodstream infections are serious conditions requiring precise bacterial identification for effective treatment. Traditional culture-based methods, while reliable, are time-consuming. The direct identification method by MALDI-TOF MS promises rapid and accurate identification directly from positive blood cultures.
View Article and Find Full Text PDFThe Effectiveness and Safety of the Short-Course Therapy in Liver Transplant Recipients With Uncomplicated Gram-Negative Bacteremia: A Retrospective Study.
Transpl Infect Dis
December 2024
Department of Infectious Diseases, The University of Tokyo Hospital, Tokyo, Japan.
Introduction: The appropriate duration of therapy for uncomplicated gram-negative bloodstream infection (GN-BSI) in liver transplant (LTx) recipients remains unknown. This study aims to explore the effectiveness of a short-course antimicrobial therapy.
Methods: This retrospective study was performed in a single LTx center in Japan.
Differential Regulatory Effects of Probiotics on Bone Metabolism by the Status of Bone Health and Delivery Route.
Probiotics Antimicrob Proteins
December 2024
Department of Oral Microbiology and Immunology, and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Probiotics are known to have favorable effects on human health. Nevertheless, probiotics are not always beneficial and can cause unintended adverse effects such as bacteremia and/or inflammation in immunocompromised patients. In the present study, we investigated the effects of probiotics on the regulation of bone metabolism under different health conditions and delivery routes.
View Article and Find Full Text PDFA Rare Bacteremia in a Patient With Osteomyelitis and Sacral Ulcer: A Case Report of Tissierella praeacuta and Parvimonas micra.
Cureus
November 2024
General Surgery, Brookdale University Hospital Medical Center, New York, USA.
and are anaerobic bacteria rarely encountered in clinical practice, making their identification in bacteremia significant. These organisms are typically found in the human gut and oral flora and are generally considered low-virulence. However, in patients with compromised immunity or significant comorbidities, they can lead to severe infections, including bacteremia.
View Article and Find Full Text PDFFlavonifractor plautii bacteremia following bacterial translocation from the gut: A case report and literature review.
J Infect Chemother
December 2024
Department of Infectious Diseases, Nagoya University Hospital, Aichi, Japan; Department of Infectious Diseases, Nagoya University Graduate School of Medicine, Aichi, Japan.
A 75-year-old male, hospitalized with back pain, remained hospitalized for tests for unexplained colitis, which was diagnosed as inflammatory bowel disease unclassified and treated with antibiotics and prednisolone, resulting in Clostridioides difficile colitis. Therefore, antibiotics were discontinued, and oral metronidazole treatment was initiated; however, as the patient's fever persisted, blood cultures were performed. An anaerobic bottle of blood culture turned positive the following day.
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