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Gut colonization of suppresses colitis-associated colon cancer development.
Microbiol Spectr
January 2025
Institute of Biological Chemistry, Academia Sinica, Taipei City, Taiwan.
Colon cancer development may be initiated by multiple factors, including chronic inflammation, genetic disposition, and gut dysbiosis. The loss of beneficial bacteria and increased abundance of detrimental microbes exacerbates disease progression. () is a human gut microbe, and its colon colonization is enhanced by a seaweed-supplemented diet.
View Article and Find Full Text PDFIntroduction to the special issue: A festschrift for Janice Kiecolt-Glaser - At the origin of stress and immunity.
Compr Psychoneuroendocrinol
November 2024
Department of Psychological Sciences, Rice University, Houston, TX, USA.
This special issue of pays tribute to Janice Kiecolt-Glaser's groundbreaking career and marks her well-earned retirement. As a leader in human psychoneuroimmunology (PNI), Kiecolt-Glaser transformed the domain by showing that everyday stressors, along with significant life events, can significantly affect the immune system. Her groundbreaking research on informal dementia caregivers revealed the detrimental effects of chronic psychological stress, including delayed wound healing, virus reactivation, heightened proinflammatory cytokine levels, and weakened vaccine responses.
View Article and Find Full Text PDFC3/C3aR Bridges Spinal Astrocyte-Microglia Crosstalk and Accelerates Neuroinflammation in Morphine-Tolerant Rats.
CNS Neurosci Ther
January 2025
Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Aims: Communication within glial cells acts as a pivotal intermediary factor in modulating neuroimmune pathology. Meanwhile, an increasing awareness has emerged regarding the detrimental role of glial cells and neuroinflammation in morphine tolerance (MT). This study investigated the influence of crosstalk between astrocyte and microglia on the evolution of morphine tolerance.
View Article and Find Full Text PDFComprehensive multi-omics, behavioral and morphological analysis of the hazards of nano-plastics in mice with internal carotid artery occlusion.
Ecotoxicol Environ Saf
January 2025
Department of Neurosurgery, Tangdu Hospital, Airforce Military Medical University, Xi'an, Shaanxi, China. Electronic address:
Accumulation of nanoplastics (NPs) poses a severe threat to the homeostasis of the internal environment in patients with chronic diseases. The effects of NP contamination on health in chronically ill populations must urgently be elucidated. In this study, NPs injected via the tail vein were distributed in the brain and internal organs in a mouse model of chronic internal carotid occlusion.
View Article and Find Full Text PDFDietary purslane (Portulaca oleracea L.) leaf powder maintains growth and intestinal health in Oreochromis niloticus under chronic water-borne cadmium exposure by strengthening the gut barriers, modulating the intestinal nutrient transporters, and relieving oxidative stress.
Fish Physiol Biochem
January 2025
Department of Biological Sciences, College of Science, University of Jeddah, P.O. Box 80327, Jeddah 21589, Saudi Arabia.
High cadmium (Cd) concentrations pose a threat to aquatic life globally. This study examined the efficiency of adding purslane (Portulaca oleracea L.) leaf powder (PLP) to Oreochromis niloticus diets on Cd's negative effects.
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