[Peanut sensitization and oily solution vitamin preparations].

Arch Pediatr

Hôpital de jour, service PB, Paris, France.

Published: January 1995

Background And Methods: Early sensitization to peanut can occur through milk formulas which contain peanut oil. Thus, the groundnut allergens in relation to the early feeding have been systematically tested in all children referred to the paediatric allergy unit for symptoms not related to peanut allergy.

Results: Out of 102 children, 4 to 35 months old, 19 had a positive test (weal > 3 mm). Neither breast feeding nor milk formulas changed the frequency of sensitization. On the contrary, vitamin D preparations in groundnut oil significantly increased the risk (p < 0.008). Odds ratios were 5.47 in the case of neonatal prescription, 4.82 in case of delayed prescription. Odds ratio increased to 8.25 (p < 0.04) in allergic children under two years who had received oily vitamin D preparation during their neonatal period.

Conclusions: The result suggest to leave groundnut oil out of all foods and drugs given to infants and young children, as required for infantile milk formulas.

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Source
http://dx.doi.org/10.1016/0929-693x(96)89804-6DOI Listing

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