We have developed 1H-chemical shift imaging (CSI) and functional magnetic resonance imaging (FMRI) methods on a clinical MRI system, in which metabolic and functional information can be obtained from the brain. 31P- and 1H-CSI are in clinical use. Using 1H-CSI, the peaks of N-acetylaspartate (NAA), choline (Cho) and creatine (Cr) are clearly detected in multiple small voxels. In normal children, the ratio of NAA/Cho increased after birth in different manners in different parts of the brain. The peak of NAA decreased in some disorders with brain damage or neuronal immaturity. It has been shown recently that functional activation of the cortex can be visualized with MR imaging with a blood oxygen level dependent (BOLD) effect. At an activated area, the ratio of deoxyhemoglobin to oxyhemoglobin decreased in the capillary and venous beds. Therefore, with a decrease of the effect of the T2 susceptibility from deoxyhemoglobin, the signal intensity of the activated area increased. CSI and FMRI have a unique possibility in the field of non-invasive brain analysis.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Exploration of magnetic zeolite thin film derived from coal fly ash an efficient sorbent: Application to water treatment.
J Environ Manage
January 2025
Faculty of Geology, Geophysics and Environmental Protection, AGH University of Science and Technology, Al. Mickiewicza 30, 30-059, Krakow city, Poland.
Fly ash, produced during coal combustion for energy making, which is recognized as an industrial by-product, could lead to environmental health hazards. Subsequently, fly ash found that an exceptional adsorption performance for the removal of various toxic pollutants, the adsorption capacity of fly ash might be altered by introducing physical/chemical stimulation. Successfully converting fly ash into zeolites not only recovers their disposal difficulties but also transforms unwanted materials into merchandisable products for various industrial applications.
View Article and Find Full Text PDFStructure characterization and preliminary immune activity of a glucomannan purified from Allii Tuberosi Semen.
Carbohydr Res
January 2025
College of Biology Pharmacy and Food Engineering, Shangluo University, Shangluo, Shaanxi, 726000, PR China. Electronic address:
A novel glucomannan, named ATSW-1, was obtained from Allii Tuberosi Semen by ion and gel permeation chromatography purification. Its structure was characterized using high-performance chromatography, Fourier transform infrared spectroscopy, gas chromatography-mass spectrometry, and nuclear magnetic resonance spectroscopy. The in vitro immune activities of ATSW-1 were examined using the Cell Counting Kit-8, the neutral red phagocytosis assay, and the secretion of related cytokines.
View Article and Find Full Text PDFDevelopmental trajectories of visual orienting functions in children born very or extremely preterm.
Early Hum Dev
January 2025
Vestibular and Oculomotor Research Group, Department of Neuroscience, Erasmus MC, Rotterdam, the Netherlands. Electronic address:
Background And Aims: Preterm birth increases the risk of neurodevelopmental impairments, such as Cerebral Visual Impairment (CVI), which affects visual processing. Assessing visual functions in young children is challenging with traditional methods that often rely on verbal/motor responses. The aim of the study was to investigate the developmental trajectories of Visual Orienting Functions (VOF) in children born very preterm (<32 weeks gestational age) between 2 and 5 years corrected age (CA) using eye tracking.
View Article and Find Full Text PDFMultifractal dynamic changes of spontaneous brain activity in psychiatric disorders: Adult attention deficit-hyperactivity disorder, bipolar disorder, and schizophrenia.
J Affect Disord
January 2025
School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, China; Department of Biomedical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA. Electronic address:
It is one of the strategies to study the complexity of spontaneous fluctuation of brain neurons based on resting-state functional magnetic resonance imaging (rs-fMRI), but the multifractal characteristics of spontaneous fluctuation of brain neurons in psychiatric diseases need to be studied. Therefore, this paper will study the multifractal spontaneous brain activity changes in psychiatric disorders using the multifractal detrended fluctuation analysis algorithm based on the UCLA datasets. Specifically: (1) multifractal characteristics in adult attention deficit-hyperactivity disorder (ADHD), bipolar disorder (BP), and schizophrenia (SCHZ); (2) the source of those multifractal characteristics.
View Article and Find Full Text PDFC7-T1 Full-Endoscopic Posterior Foraminotomy and Sequestrectomy Using Navigation.
Neurospine
December 2024
Departement of Neurosurgery, Sion Cantonal Hospital, Wallis, Switzerland.
The main objective of this case and video is to demonstrate the surgical technique of navigated full-endoscopic decompression and sequestrectomy at the C7-T1 level to alleviate C8 nerve root compression and manage cervicobrachialgia. Cervicobrachialgia resulting from C7-T1 disc herniation is a quite rare yet painful condition that can significantly impair motor function in the upper limb. Traditionally, open surgeries can be invasive, with prolonged recovery times and/or fusion of the level with adjacent segment disease.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!