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Evolution of ceftazidime/avibactam resistance and plasmid dynamics in OXA-48-producing Klebsiella spp. during long-term patient colonization.
Eur J Clin Microbiol Infect Dis
January 2025
UGC Microbiología and Instituto de Investigación E Innovación Biomédica de Cádiz (INIBICA), Hospital Universitario Puerta del Mar, Cádiz, Spain.
Purpose: To prospectively monitor the evolution of the resistome of OXA-48-producing Klebsiella species in a patient with long-term colonization, with a particular focus into the plasmid dynamics and the evolution of ceftazidime/avibactam resistance.
Methods: All OXA-48-producing Klebsiella spp. isolates from a single patient admitted to a hospital during seven months were prospectively collected.
Tunable Cluster Luminescence and High Quantum Yield in Amine-Modified Maleic Anhydride Polymers.
Langmuir
January 2025
The Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.
Cluster luminescent materials (CLgens) with nonconjugated structures have attracted considerable attention. However, their low quantum yield and limited emission wavelengths, which are confined to the blue-green spectrum, continue to restrict their applicability. In this study, maleic anhydride polymer chains were modified with -tristyrylene-1,2-diamine (TPM-NH), creating a secondary donor-acceptor structure through freely rotatable phenyl groups and amino-anhydride interactions.
View Article and Find Full Text PDFAssociations between blood donors, component modifications, and the alloimmunization of transfusion recipients.
Transfusion
January 2025
Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Background: Prior studies have evaluated transfusion recipient variables impacting red blood cell (RBC) alloimmunization, but few focused on potentially modifiable blood donor or blood component variables.
Study Design And Methods: Data from the Recipient Epidemiology and Donor Evaluation Study (REDS)-III, which links donor, component, and patient data in an integrated database, were accessed. For any given RBC unit with sufficient blood donor and component data, we determined if the transfusion recipient experienced a new RBC alloimmunization event ("case") within 16 weeks of the transfusion or not ("control").
A Cd-based crystalline network material: catalytic properties and post-synthetic metal-ion metathesis with enhanced stability and gas sorption behaviour.
Dalton Trans
January 2025
Department of Chemistry, Jadavpur University, Jadavpur, Kolkata-700 032, West Bengal, India.
This study presents the synthesis of a Cd(II) based hydrophobic three dimensional crystalline network material (CNM), [Cd(L)(LH)(bpe)], {L = {4,4'-(hexafluroisopropylidine)bis(benzoate)} and 1,2-di(4-pyridyl) ethylene (bpe)}, 1(Cd), by employing the slow-diffusion method. The three-dimensional structure of 1(Cd) was determined by single crystal X-ray diffraction and characterized by powder X-ray diffraction (PXRD), FT-IR spectroscopy and thermogravimetric analysis (TGA). Subsequently, post-synthetic modification of 1(Cd) with Cu(II) at room temperature led to the formation of isostructural 1(Cu) with partial substitution.
View Article and Find Full Text PDFUntreated and uncontrolled hypertension in Japanese patients with spontaneous intracerebral hemorrhage.
Hypertens Res
January 2025
Division of Neurology, Department of Medicine, Jichi Medical University School of Medicine, Tochigi, Japan.
Hypertension (HT) is the most attributable and modifiable risk factor for spontaneous intracerebral hemorrhage (SICH). However, epidemiological data on blood pressure (BP) control before SICH and its relationship to patient lifestyles are lacking. This study prospectively enrolled patients with acute SICH from six stroke centers in Tochigi, Japan.
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