Using a combination of X-ray diffraction data from oriented films and multilamellar liposomes of 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) in the subgel phase, we have established the presence of a 2D molecular lattice containing two lipid molecules. The proposed 2D lattice is consistent with all the X-ray diffraction data on the subgel phase of DPPC available in the literature. In this phase, the DPPC molecules are ordered in the plane of the bilayer and are also found to be positionally correlated across a single bilayer but not with those in adjacent bilayers. We also present the possible molecular arrangements for the proposed lattice.
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