Objective: This in vitro study was designed to assess the z-axis resolving capabilities of reconstructed helical CT scans obtained with various imaging parameters versus those of conventional CT scans and the effect of decreasing slice index on the z-axis resolution of helical CT.
Materials And Methods: A z-axis line-pair phantom was imaged using conventional nonoverlapped CT scans, conventional CT scans that overlapped by 50%, and helical CT scans with pitches of 1.0 and 1.5. All helical images were reconstructed at comparable slice indexes (image indexes of 2.0, 1.0, and 0.5 mm for pitch = 1.0, and image indexes of 3.0, 1.5, and 0.75 mm for pitch = 1.5). Midline coronal and sagittal reconstructed images were obtained to allow standardized visualization of line pairs. The reconstructed images were reviewed separately by 10 radiologists.
Results: The overall z-axis resolution of reconstructed helical CT scans equaled or exceeded that of nonoverlapped conventional CT scans in all cases and equaled that of 50% overlapped conventional CT scans in 75% of cases. The 1.0-pitch helical sequences showed improved z-axis resolution with decreasing slice index. No statistically significant improvement in z-axis resolution could be determined by the observers for 1.5-pitch sequences with decreasing slice index.
Conclusion: The use of helical CT with a pitch of 1.0 or 1.5 and an increased slice index can improve the z-axis resolution of reconstructed images when compared with nonoverlapped conventional CT and frequently equals the resolution of 50% overlapped conventional CT. This improvement in z-axis resolution should improve the appearance of reconstructed images (as used in CT angiography and three-dimensional imaging) by reducing partial volume artifacts while affording faster scanning at a reduced skin-surface radiation dose.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.2214/ajr.164.5.7717248 | DOI Listing |
Conf Comput Vis Pattern Recognit Workshops
June 2024
Volumetric biomedical microscopy has the potential to increase the diagnostic information extracted from clinical tissue specimens and improve the diagnostic accuracy of both human pathologists and computational pathology models. Unfortunately, barriers to integrating 3-dimensional (3D) volumetric microscopy into clinical medicine include long imaging times, poor depth/z-axis resolution, and an insufficient amount of high-quality volumetric data. Leveraging the abundance of high-resolution 2D microscopy data, we introduce masked slice diffusion for super-resolution (MSDSR), which exploits the inherent equivalence in the data-generating distribution across all spatial dimensions of biological specimens.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2024
Department of Chemical Engineering, Stanford University, Stanford, CA 94305.
Stereolithography enables the fabrication of three-dimensional (3D) freeform structures via light-induced polymerization. However, the accumulation of ultraviolet dose within resin trapped in negative spaces, such as microfluidic channels or voids, can result in the unintended closing, referred to as overcuring, of these negative spaces. We report the use of injection continuous liquid interface production to continuously displace resin at risk of overcuring in negative spaces created in previous layers with fresh resin to mitigate the loss of Z-axis resolution.
View Article and Find Full Text PDFZookeys
July 2024
Centre for Biodiversity Genomics, University of Guelph, 50 Stone Road East, Guelph, Ontario, N1G 2W1, Canada University of Guelph Guelph Canada.
Large-scale digitization of natural history collections requires automation of image acquisition and processing. Reflecting this fact, various approaches, some highly sophisticated, have been developed to support imaging of museum specimens. However, most of these systems are complex and expensive, restricting their deployment.
View Article and Find Full Text PDFJpn J Radiol
November 2024
Department of Physics, Faculty of Science, University of Guilan, 41635-1914 Rasht, Iran.
Purpose: Collimator-detector response function (CDRF) of a SPECT scanner refers to the image generated from a point source of activity. This research aims to characterize the CDRF of a breast-dedicated SPECT imager equipped with a lofthole collimator using GATE Monte Carlo simulation.
Materials And Methods: To do so, a cylindrical multi-lofthole collimation system with lofthole apertures dedicated to breast imaging was modeled using the GATE Monte Carlo simulator.
J Neurochem
September 2024
Department of Neurochemistry and Molecular Cell Biology, School of Medicine, and Graduate School of Medical/Dental Sciences, Niigata University, Niigata, Japan.
A growth cone is a highly motile tip of an extending axon that is crucial for neural network formation. Three-dimensional-structured illumination microscopy, a type of super-resolution light microscopy with a resolution that overcomes the optical diffraction limitation (ca. 200 nm) of conventional light microscopy, is well suited for studying the molecular dynamics of intracellular events.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!