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Folliculitis might be associated with pathergy-positivity in patients with Behçet syndrome.
Medicine (Baltimore)
March 2024
Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul, Turkey.
Pathergy test indicates nonspecific hyper-reactivity of the skin to aseptic trauma in Behçet syndrome (BS) and is considered as an adjunctive diagnostic test with a good specificity albeit with low sensitivity. We tested the hypothesis that a relationship exists between active clinical manifestations of BS and the pathergy-positivity when performed simultaneously. Pathergy test and detailed dermatologic examination were done in 105 BS patients (60M/45F); who were seen consecutively at the multi-disciplinary BS outpatient clinic in a single tertiary center.
View Article and Find Full Text PDFFunctional validation of co-culture model of human keratinocytes and neuronal cell line for sensitive skin by using transient receptor potential channel vanilloid subfamily member 1 antagonist.
Skin Res Technol
January 2023
Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.
Background: Sensitive skin is a subjective cutaneous hyper-reactivity that occurs in response to various innocuous stimuli. Keratinocytes have recently been shown to participate in sensory transduction by releasing many neuroactive molecules that bind to intra-epidermal free nerve endings and modulate nociception. In the literature, the characterization of these interactions has been based on the co-culture of keratinocyte and mammalian-origin neuronal cell lines.
View Article and Find Full Text PDFThe diagnostic role of pathergy test in patients with Behçet's disease from the Western Europe.
Intern Emerg Med
January 2023
Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic and Rheumatology-Ophthalmology Collaborative Uveitis Center, Policlinico ''Le Scotte'', University of Siena, Viale Bracci 16, 53100, Siena, Italy.
The aim of the study is to evaluate the frequency and features of positive pathergy test (PPT) in Italy, its role in the diagnosis of Behçet's disease (BD), and any association with other BD-related manifestations. 52 BD patients, 52 patients with axial spondyloarthritis (ax-SpA), and 26 healthy controls (HCs) underwent intradermal injection of normal saline and intradermal needle soaked with fresh self-saliva. The results of pathergy tests were statistically analysed in the light of demographic, clinical, and therapeutic features of subjects enrolled.
View Article and Find Full Text PDFEmergency vaccination of cattle against lumpy skin disease: Evaluation of safety, efficacy, and potency of MEVAC LSD vaccine containing Neethling strain.
Vet Res Commun
June 2023
Department of Animal Medicine (Branch of Infectious Diseases), Faculty of Veterinary Medicine, Damanhour University, 22511, El‑Beheira, Egypt.
Lumpy skin disease (LSD) is an emerging disease of cattle causing significantly high economic losses. Control of LSD depends on the use of homologous attenuated LSD virus strains isolated originally from South Africa (the Neethling strain). The virus belongs to the genus Capripoxvirus, which includes sheep pox virus and goat pox virus.
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