Treatment reproducibility is a major criterion of quality assurance in radiation therapy. During each course, the same dose should be delivered in the same volume of irradiation. Today, portal imaging devices can be used routinely to check and correct patient positioning before much of the daily irradiation has been delivered. In this study we used the Portal Vision Varian (PVV) system during pelvic irradiation in 16 patients. This device can automatically acquire portal images in the first seconds of each course. Observed discrepancies are directly classified by the radiation oncologist according to their type (cranio-caudal, lateral, antero-posterior) and severity (correction of patient positioning is necessary or not). In case of error, patient positioning is corrected before the end of irradiation. Of the 922 portals analysed with PVV, 901 could be analysed (97%). Two hundred and ninety-nine positioning discrepancies were observed (33%) with 59 of them leading to correction (6%). Most of the time, these errors concerned antero-posterior portals. Finally, each patient had an average of 18 to 19 discrepancies which were mainly of no importance for treatment quality. Nevertheless, real errors leading to correction were observed in 14 patients (88%) with an average of four per patient. In some patients many errors occurred, while in others only a few. These shifts were not related to patient weight and thickness but probably a portal dimension. In summary, we think that during pelvic irradiation a portal imaging device should be used daily to improve treatment quality. This system can help the radiation oncologist to discover many positioning errors (an average of four) in the majority of patients (88%) and to correct them before the end of irradiation.
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Heliyon
January 2025
Department of General Surgery, Fribourg Cantonal Hospital, 1700, Fribourg, Switzerland.
Background: Current management of patients with borderline resectable pancreatic adenocarcinoma (BR-PDAC) depends on the degree of involvement of the major arterial and venous structures. The aim of this study was to evaluate 3D segmentation and printing to predict tumor size and vascular involvement of BR-PDAC to improve pre-operative planning of vascular resection and better select patients for neoadjuvant therapy.
Methods: We retrospectively evaluated 16 patients with BR-PDAC near vascular structures who underwent pancreatoduodenectomy (PD) with or without vascular resection between 2015 and 2021.
Front Med (Lausanne)
January 2025
Department of General Surgery, Baskent University, Istanbul, Türkiye.
Introduction: Various reports have confirmed that low skeletal muscle mass, a proxy marker of sarcopenia, can be a risk factor for surgical and oncological outcomes in colon cancer. We aimed to investigate the effects of skeletal muscle mass index (SMMI) on postoperative complications, overall survival (OS), and disease-free survival (DFS) in older patients with colon cancer who underwent elective curative colon resections.
Materials And Methods: Patients over 65 years old with stage I-III colon cancer who underwent elective curative colon resections between January 2015 and December 2023 were included in this single-center retrospective longitudinal study.
J Med Case Rep
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Department of Hepatic Biliary Pancreatic Medicine, First Hospital of Jilin University, 1 Xinmin Avenue, Changchun, 130021, China.
Background: Dyskeratosis congenita is a rare genetic disease due to telomere biology disorder and characterized by heterogeneous clinical manifestations and severe complications. "Porto-sinusoidal vascular disease" has been recently proposed, according to new diagnostic criteria, to replace the term "idiopathic non-cirrhotic portal hypertension." TERT plays an important role in telomeric DNA repair and replication.
View Article and Find Full Text PDFBMC Cancer
January 2025
PET/CT center, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, 127 Dongming Road, Zhengzhou, Henan, 450008, China.
Objective: To investigate the predictive value of machine learning-based PET/CT radiomics and clinical risk factors in predicting interim efficacy in patients with follicular lymphoma (FL).
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Rofo
January 2025
Faculty of Medicine and University Hospital Cologne, Department of Diagnostic and Interventional Radiology, University Hospital Cologne, Cologne, Germany.
Online survey about the current status of CT protocols in hepatocellular carcinoma (HCC) in the year 2023/2024. Moreover, the usage of structured reporting using LI-RADS and mRECIST was surveyed and the results were compared with a survey from 2020.Radiologists working in outpatient or inpatient care in Germany were invited.
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