Under experimental acute pancreatitis of rats, certain changes were revealed in the liver histological structure, hepatocyte population composition, intensity of hepatocyte DNA-synthesis, their proliferation, and in hepatocyte glycogen contents. These changes reflect a two-step process of hepatocyte activation. This results well compares with the earlier evidence on changes in pancreatic cell population under acute pancreatitis. The role of hepatocyte protective reactions during regenerative process in pancreas, under acute pancreatitis and its transition into chronic condition, is discussed.
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