All dosimetry protocols for calibrating the output of electron beams recommend the use of parallel-plate ionization chambers, but the method of determining their value of Ngas is a matter of concern. The AAPM Protocol (TG 21) recommends a direct comparison with a calibrated cylindrical chamber in phantom at dmax with the highest available electron energy beam. This must be done by the user. Since all calibration laboratories traditionally use 60Co for megavoltage chamber calibrations, two alternate procedures based on exposures in-air, or in-phantom, have been proposed. All methods use correction factors in the data reduction. To verify the consistency of the three methods, we have measured Ngas using each of these techniques for six of the most commonly used and commercially-available parallel-plate ionization chambers. The paired cylindrical and parallel-plate ionization chambers, and phantom materials/buildup caps were matched to the wall composition of the plane chambers, as recommended in TG 39. A 22 MeV electron beam was used for the electron irradiations. The ionization chambers were then taken to an Accredited Dosimetry Calibration Laboratory (ADCL), where 60Co calibrations were performed. The results demonstrate that, by using the appropriate correction factors for the chambers described in this work, all three methods yield values for Ngas that are within 1% of each other.
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http://dx.doi.org/10.1118/1.597180 | DOI Listing |
Int J Part Ther
March 2025
Institute of Medical Physics and Radiation Protection, University of Applied Sciences, Giessen, Germany.
Purpose: The spot size of scanned particle beams is of crucial importance for the correct dose delivery and, therefore, plays a significant role in the quality assurance (QA) of pencil beam scanning ion beam therapy.
Materials And Methods: This study compares 5 detector types-radiochromic film, ionization chamber (IC) array, flat panel detector, multiwire chamber, and IC-for measuring the spot size of proton and carbon ion beams.
Results: Variations of up to 30% were found between detectors, underscoring the impact of detector choice on QA outcomes.
Tech Innov Patient Support Radiat Oncol
March 2025
Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Tokushima 770-8503, Japan.
Purpose: This study aims to compare treatment plans created using RapidPlan and PlanIQ for twelve patients with prostate cancer, focusing on dose uniformity, dose reduction to organs at risk (OARs), plan complexity, and dose verification accuracy. The goal is to identify the tool that demonstrates superior performance in achieving uniform target dose distribution and reducing OAR dose, while ensuring accurate dose verification.
Methods: Dose uniformity in the planning target volume, excluding the rectum, and dose reduction in the OARs (the rectum and bladder) were assessed.
J Neurosci Methods
January 2025
Cognitive Neuroscience Laboratory, German Primate Center - Leibniz Institute for Primate Research, Goettingen, Germany; Faculty of Biology and Psychology, University of Goettingen, Goettingen 37077 Germany.
Background: Neuronal activity is modulated by behavior and cognitive processes. The combination of several neurotransmitter systems, acting directly or indirectly on specific populations of neurons, underlie such modulations. Most studies with non-human primates (NHPs) fail to capture this complexity, partly due to the lack of adequate methods for reliably and simultaneously measuring a broad spectrum of neurotransmitters while the animal engages in behavioral tasks.
View Article and Find Full Text PDFIndian J Nucl Med
November 2024
Center for Research and Production of Radioisotopes, Dalat Nuclear Research Institute, Vietnam Atomic Energy Institute (VINATOM), Da Lat City, Lam Dong Province, Vietnam.
Aims: This study aimed to evaluate the principal technical characteristics of a well-type gas-filled ionization chamber dose calibrator used in measuring radiopharmaceutical activity, namely accuracy, repeatability, and linearity. Furthermore, this work also explored the correlation between the device's response and the position and volume of the radiopharmaceutical I-131.
Materials And Methods: Experimental measurements were conducted on the ATOMLAB 500 dose calibrator using NIST traceable Cs-137 source to determine the accuracy and repeatability.
Anal Chim Acta
January 2025
University Regensburg, Institute of Analytical Chemistry, Universitätsstrasse 31, 93053, Regensburg, Germany. Electronic address:
Background: The demand for lithium-ion cells in the automotive industry is rapidly growing due to the increasing electrification of the transportation sector. The electrolyte composition plays a critical role in determining the lifetime and performance of these large-format cells. Additionally, advancements in this field are leading to frequent changes in both electrode materials and electrolyte formulations.
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