A new phenomenon of small vessel transformation is observed electron microscopically in the biopsies of normal and extended human skin as well as granulation tissue. This phenomenon appears to reflect an important mechanism in physiological and reparative regeneration of the dermis. It manifests in that endotheliocytes and pericytes may become the source of new cell formation, for example, fibroblasts. This process of vessel "destruction" is closely associated with the formation of new capillaries and precapillaries.
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