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Arterial compliance (AC) is an important cardiovascular parameter characterizing mechanical properties of arteries. AC is significantly influenced by arterial wall structure and vasomotion, and it markedly influences cardiac load. A new method, based on a two-element Windkessel model, has been recently proposed for estimating AC as the ratio of the time constant T of the diastolic blood pressure decay and peripheral vascular resistance derived from clinically available stroke volume measurements and selected peripheral blood pressure parameters which are less prone to peripheral distortions.
View Article and Find Full Text PDFEffect of plaque micro-watershed changes on carotid atherosclerosis.
Comput Methods Programs Biomed
January 2025
Dalian University of Technology Affiliated Central Hospital, Dalian 116024, China.
Objective: The study aims to elucidate the mechanisms underlying plaque growth by analyzing the variations in hemodynamic parameters within the plaque region of patients' carotid arteries before and after the development of atherosclerotic lesions.
Methods: The study enrolls 25 patients with common carotid artery stenosis and 25 with tandem carotid artery stenosis. Based on pathological analysis, three-dimensional models of the actual blood vessels before and after the lesion are constructed for two patients within a two-year period.
Influence of Geometric Parameters on The Hemodynamic Characteristics of The Vertebral Artery.
J Biomech Eng
January 2025
State Key Laboratory of Clean Energy Utilization, Zhejiang University, Yuquan Campus, 38 Zheda Road, Hangzhou 310027, Zhejiang, China; Shanghai Institute for Advanced Study of Zhejiang University, Zhangjiang Guochuang Center phase, No.799, Dangui Road, Shanghai 200120, China.
The carotid and vertebral arteries are principal conduits for cerebral blood supply and are common sites for atherosclerotic plaque formation. To date, there has been extensive clinical and hemodynamic reporting on carotid arteries; however, studies focusing on the hemodynamic characteristics of the vertebral artery (VA) are notably scarce. This article presents a systematic analysis of the impact of VA diameter and the angle of divergence from the subclavian artery (SA) on hemodynamic properties, facilitated by the construction of an idealized VA geometric model.
View Article and Find Full Text PDFIntermittent negative pressure influences popliteal artery shear rate during supine and sitting postures.
Vasa
January 2025
Faculty of Medicine, University of Oslo, Norway.
Intermittent negative pressure is an emerging treatment for lower limb vascular disease but the specific physiological effects, particularly upon large artery haemodynamics are unclear. This study examined the influence of intermittent negative pressure upon popliteal artery shear rate during both supine and sitting postures. Eleven healthy participants (5 female; age: 28.
View Article and Find Full Text PDFEvaluation of Coronary Artery Calcium Score (CACS) in Dipper and Non-Dipper Hypertensive Patients with Moderate and High Cardiovascular Disease Risks.
Medicina (Kaunas)
December 2024
Department of Public Health, Faculty of Medicine, Ondokuz Mayis University, 55270 Samsun, Turkey.
: Hypertension is typically classified into two main groups, "dipper" and "non-dipper", based on nocturnal blood pressure decline. The coronary artery calcium score (CACS) is an essential biomarker used to assess the presence and severity of coronary artery disease (CAD). This study aims to demonstrate the relationship between CACS and hypertensive patients with moderate-to-high cardiovascular disease (CVD) risk classified as either dipper or non-dipper.
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