The contribution of specially trained developmental nurses (DNs) to the accuracy of developmental screening in well-baby units was assessed. Of 13,580 children between two and 48 months of age, the well-baby clinic identified definitive developmental delay in 310, and 357 children were classified as 'questionable'. After DN assessment at 12 months follow-up, only 31 per cent of the questionable group required referral to the Child Development Centre (CDC). Comparison of the original queried recommendations to the CDC with the DN's recommendation indicated a false-positive and -negative rate of 60 and 20 per cent, respectively. This procedure resulted in false-positive and -negative screening accuracies of 1.2 and 6 per cent, respectively, for the total cohort of children screened. The economic and clinical advantages of this model are discussed.
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http://dx.doi.org/10.1111/j.1469-8749.1993.tb11628.x | DOI Listing |
Acad Radiol
January 2025
Guangxi Medical University, Nanning, Guangxi 530021, China (C.Z., D.H., B.W., S.W., Y.S., X.W.); Guangxi Key Laboratory of Enhanced Recovery After Surgery for Gastrointestinal Cancer, Nanning, Guangxi 530021, China (C.Z., D.H., B.W., S.W., Y.S., X.W.); Department of Gastrointestinal Gland Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China (D.H., X.W.). Electronic address:
Rationale And Objectives: Accurate preoperative pathological staging of gastric cancer is crucial for optimal treatment selection and improved patient outcomes. Traditional imaging methods such as CT and endoscopy have limitations in staging accuracy.
Methods: This retrospective study included 691 gastric cancer patients treated from March 2017 to March 2024.
Alzheimers Dement
December 2024
Washington University School of Medicine, St. Louis, MO, USA.
Background: P-tau217 has emerged as a compelling alternative to long-established p-tau181 to accurately measure tau modifications in biofluids in response to brain Abeta and tau deposition in Alzheimer's disease (AD). Understanding the specificity and significance of p-tau217 changes over AD stages is critical to interpret its potential response to treatments against Abeta and tau aggregation.
Methods: We measured p-tau217 phosphorylation by mass spectrometry.
Alzheimers Dement
December 2024
Wisconsin Alzheimer's Institute, University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Background: The Clinical Dementia Rating Scale (CDR) is a gold standard metric for staging the nature and severity of global cognitive and functional impairment in Alzheimer's disease (AD) and other dementias. Prior evidence from older and/or smaller samples suggests that The Quick Dementia Rating System (QDRS) informant questionnaire provides results comparable to the CDR and can be completed in just 3-5 minutes, sans a trained clinician or rater. This study aimed to: 1) investigate concordance between the QDRS-derived global CDR ("QDRS-global"; Galvin, 2015) and CDR-global scores; 2) examine item-level QDRS/CDR agreement; and (3) evaluate QDRS-global/CDR-global concordant/discordant groups against concurrent Preclinical Alzheimer's Cognitive Composite (PACC3) performance.
View Article and Find Full Text PDFUrine drug screening is carried out on numerous automated analysis platforms using enzyme-linked immunosorbent assays. While these methods are rapid, they often lack specificity. We report the case of a 5-year-old child treated for Dravet disease and hospitalized for clonic seizures.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
January 2025
Southern California College of Optometry at Marshall B Ketchum University, Fullerton, California, United States.
Purpose: When treating amblyopia, it is important to define when visual acuity (VA) is no longer improving (i.e., stable) because treatment decisions may be altered based on this determination.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!