AI Article Synopsis
- The immune status of 18 children, some vaccinated and some not, living in a parotitis outbreak area was monitored over time.
- By days 10-20, 88.9% of children showed specific antibodies, while 55.6% had memory antigen-reactive cells; however, 66.7% exhibited temporary T-immunodeficiency.
- Despite no visible cases of parotitis, immunologic studies indicated the presence of the wild type virus and identified 2 cases of unrecognized epidemic parotitis.
Article Abstract
The immune status of 18 children previously vaccinated or not with live parotitis vaccine and living in a focus of parotitis was tested over time. Specific antibodies were found in the blood sera or nasal secretion of 88.9% children by follow-up days 10-20, and memory antigen-reactive cells were forming in 55.6%. Functional temporary T-immunodeficiency was observed at the same period in 66.7% children. Although there were no cases of clinically apparent epidemic parotitis, immunologic studies confirmed the circulation of wild type virus. Immunologic studies detected 2 cases of inapparent course of epidemic parotitis.
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