Objective: To determine the degree and the frequency of the nailfold capillary abnormalities and to correlate these with clinicolaboratory variables of Behçets disease.
Methods: A stereomicroscope was applied to study the nutritional skin capillaries of the nailfolds. Stages 0, A, B and C (Fagrell's classification) were distinguished.
Results: In 40 healthy subjects capillary abnormalities (stage A) were detected in 7%. In 33 of our patients abnormal nailfold capillary findings (stages A, B, C) were noted in 75%. The stage of capillary abnormalities was significantly correlated with skin manifestations (p = 0.03), arthritis/arthralgia (p = 0.04), and pathergy test (p = 0.04). The correlation between stages 0 and A and eye involvement was not significant (p = 0.08). Disease duration was longer in patients of stage C than in stage 0 but this difference was also not significant (p < 0.10).
Conclusion: Using a noninvasive method we detected nailfold capillary abnormalities in the majority of our patients.
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Hematology
December 2025
Division of Hematology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, and King Chulalongkorn Memorial Hospital, Thai Red Cross, Bangkok, Thailand.
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Department of Radiology and Radiotherapy, School of Medicine, College of Health Sciences Makerere University Kampala Uganda.
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January 2025
State Key Laboratory of Environment Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing, China.
Human health is being threatened by environmental microplastic (MP) pollution. MPs were detected in the bloodstream and multiple tissues of humans, disrupting the regular physiological processes of organs. Nanoscale plastics can breach the blood-brain barrier, leading to neurotoxic effects.
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