Polyethylene wear increasingly has been blamed for osteolysis and granuloma formation after total joint arthroplasty. The authors evaluated the wear difference between bearing surfaces of stainless steel, cobalt chrome, and titanium alloy. They also compared cemented all-polyethylene molded cups with cemented metal-backed molded acetabular cups. These were compared with molded and machined polyethylene cups. Two patient groups were matched individually for gender, age, weight, and length of followup. Analyses were done using the technique of Livermore et al. The bearing surface evaluation consisted of 3 groups after matching, leaving 77 patients per group. Results showed linear wear rates of 0.06 mm per year, 0.05 mm per year, and 0.08 mm per year for stainless steel, cobalt chrome, and titanium alloy, respectively. The comparison between cemented molded metal-backed and nonmetal-backed acetabular components was not matched, with 134 metal-backed and 99 nonmetal-backed components. Results showed linear wear rates of 0.011 mm per year in the metal-backed group and 0.08 mm per year in the nonmetal-backed group. Results were statistically significant. These results indicate that the metal composition of the femoral bearing surface has minimal, if any, effect on the linear polyethylene wear rate. The method of polyethylene fabrication and the use of metal backing had a significant effect on the polyethylene wear rate in these patient groups. These results suggest that the compression-molded all-polyethylene acetabular component may be optimal for reducing polyethylene wear in total hip arthroplasty.
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J Mech Behav Biomed Mater
January 2025
Division of Orthopaedic Surgery, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada; Department of Medical Biophysics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada. Electronic address:
Background: The risk of early revision of total hip arthroplasty (THA) for polyethylene wear is now low, but there remains a need to perform wear measurements in patients for clinical surveillance. The gold standard of wear measurements has been radiostereometric analysis (RSA), which has limited availability. The use of computed tomography (CT) to perform THA wear measurement was described a decade ago and found to have acceptable accuracy and precision, but high radiation dose was a concern.
View Article and Find Full Text PDFBiomedicines
January 2025
Department of Orthopedic Surgery, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, Kita-15, Nish-7, Kita-ku, Sapporo 060-8638, Japan.
Periprosthetic osteolysis is the primary cause of arthroplasty failure in the majority of patients. Mechanistically, wear debris released from the articulating surfaces of a prosthesis initiates local inflammation and several modes of regulated cell death programs, such as ferroptosis, which represents a promising therapeutic target in various chronic inflammatory diseases. Thus, the current study aimed at exploring the therapeutic potential of targeting ferroptosis in a polyethylene-wear-debris-induced osteolysis model.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Orthopaedics, Liaocheng People's Hospital, Liaocheng, Shandong, P.R. China.
Background: Vitamin E-diffused highly cross-linked polyethylene (HXLPE/Vit E) is a relatively advanced material used in total hip arthroplasty (THA) but whether it shows superiority is unclear.
Objective: This meta-analysis was performed to investigate the effect of HXLPE/Vit E liners in THA.
Methods: Medline/PubMed, Embase and Cochrane Library databases were searched to retrieve studies assessing the efficacy of HXLPE/Vit E liners in THA with the design of a randomized, controlled trial.
Environ Res
January 2025
Southern California Coastal Water Research Project, Costa Mesa, CA, 92626, United States.
The concentration, character, and distribution of microplastics in coastal marine environments remain poorly understood, with most research focusing on the abundance of microplastics at the sea surface. To address this gap, we conducted one of the first comprehensive assessments of microplastic distribution through the marine water column and benthic sediment during the wet and dry season in the coastal waters of the San Pedro Bay Southern California, USA. Microplastic concentrations in the water column did not vary significantly across season but were significantly higher in nearshore environments and at the surface of the water column.
View Article and Find Full Text PDFArthroplast Today
December 2024
Hospital Pavia Arecibo, Arecibo Orthopedic Institute, Arecibo, PR, USA.
Synovial fistula of the knee occurs when a defect in the joint capsule creates a connection between skin, bursa, and a near tissue, manifesting as an opening with continuous draining fluid or a cyst. This is a case of an 80-year-old male who developed a synovial fistula with cystic presentation 6 years after the primary total knee arthroplasty. Management included a total knee arthroplasty revision surgery with intraoperative identification of the fistula with methylene blue, and using a gelatin-thrombin matrix for closure.
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