Purpose: An ecological study was performed to test the association between coronary heart disease (CHD) mortality and smoking in Brazil. Lung cancer mortality was used as a surrogate for smoking habit.
Methods: The mortality rate for CHD (ICD-9:410-414) and lung cancer (ICD-9: 162) were determined in the following metropolitan areas: Belém, Recife, Salvador, Belo Horizonte, Rio de Janeiro, São Paulo, Curitiba and Porto Alegre for males and females between 30 and 69 year old. ANOVA test was used to compare both age-adjusted mortality rates.
Results: A positive association by ANOVA was determined only for males ages 60-69 and to age-adjusted rates.
Conclusion: The relationship between smoking and CHD mortality as determined in Brazilian cities, among men, mainly in the older ages, is a proof that tobacco control would contribute to downward trends in CHD mortality rates.
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Cureus
December 2024
Paediatrics, Maternity and Children Hospital, AlAhsa, SAU.
Background Maternal diabetes mellitus (DM) is a known risk factor for congenital heart diseases (CHDs), which are of significant concern to infants born to diabetic mothers. Compared to newborns born to non-diabetic mothers, infants born to diabetic mothers had a higher overall risk of developing congenital malformations. This association has a complex pathophysiology that includes genetic predispositions, metabolic abnormalities, and environmental factors during key stages of fetal development.
View Article and Find Full Text PDFFront Pharmacol
January 2025
State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Atherosclerotic cardiovascular disease (ASCVD) causes significant morbidity and mortality globally. Most of the chemicals specifically target certain pathways and minimally impact other diseases associated with ASCVD. Moreover, interactions of these drugs can cause toxic reactions.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Hepatobiliary Pancreatic Surgery Department, Huadu District People's Hospital of Guangzhou, Guangzhou, China.
Background: Sepsis is a life-threatening disease associated with a high mortality rate, emphasizing the need for the exploration of novel models to predict the prognosis of this patient population. This study compared the performance of traditional logistic regression and machine learning models in predicting adult sepsis mortality.
Objective: To develop an optimum model for predicting the mortality of adult sepsis patients based on comparing traditional logistic regression and machine learning methodology.
Nat Rev Cardiol
January 2025
Quebec Heart & Lung Institute, Laval University, Quebec City, Quebec, Canada.
Advances in imaging diagnostics, surgical techniques and transcatheter interventions for paediatric patients with severe congenital heart disease (CHD) have substantially reduced mortality, thereby extending the lifespan of these individuals and increasing the number of adults with complex CHD. Transcatheter interventions have emerged as an alternative to traditional open-heart surgery to mitigate congenital defects. The evolution of techniques, the introduction of new devices and the growing experience of operators have enabled the treatment of patients with progressively more complex conditions.
View Article and Find Full Text PDFAnn Pediatr Cardiol
December 2024
Department of Biostatistics, AIIMS, New Delhi, India.
Introduction: Congenital heart disease (CHD)-associated malnutrition is a systemic consequence of CHD. Dietary recommendations to fulfill nutritional requirements are lacking. This randomized controlled trial (RCT) was conducted to determine the efficacy of early enteral feeding with supplemented expressed breast milk (suppl-EBM) versus expressed breast milk (EBM) in improving the weight of postoperative cardiac surgical infants.
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