The article deals with analysis of scientific data concerning etiology, pathogenesis, clinical and roentgenologic manifestations, morphologic appearances and other aspects to precise and refine the former idea of pneumoconioses. The authors present the main principles for improved classification of pneumoconioses.
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A contemporary, multiinstitutional analysis of transcription factor lineage in pituitary adenomas: comparative study of neuroimaging, histopathology, and clinical outcomes.
J Neurosurg
March 2025
1Department of Neurological Surgery, University of Southern California, Keck School of Medicine, Los Angeles, California.
Objective: Pituitary adenomas (PAs) are common lesions that often present with endocrinopathy and/or visual symptoms. Classification of PAs has historically been based on functional status and histopathological staining of anterior pituitary hormones. In 2017, the WHO revised the classification of PAs, establishing cell lineages identified by the transcription factors (TFs) PIT1, TPIT, and SF1.
View Article and Find Full Text PDFWhat is the rate and timing of salvage surgery after operative treatment of talus fractures?
J Orthop Trauma
March 2025
Harborview Medical Center, University of Washington Department of Orthopaedics and Sports Medicine.
Objectives: To report on the short-term, mid-term, and long-term rates of salvage treatment after operative treatment of talus fractures.
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Surface-Induced Unfolding Reveals Unique Structural Features and Enhances Machine Learning Classification Models.
Anal Chem
March 2025
Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Native ion mobility-mass spectrometry combined with collision-induced unfolding (CIU) is a powerful analytical method for protein characterization, offering insights into structural stability and enabling the differentiation of analytes with similar mass and mobility. A surface-induced dissociation (SID) device was recently commercialized, enabling broader adoption of SID measurements and surface-induced unfolding (SIU). This study evaluates SIU, benchmarking its reproducibility and performance against CIU on a Waters CyclicIMS ion mobility-mass spectrometer.
View Article and Find Full Text PDFBackground And Objectives: Whether thrombectomy compared with best medical treatment (BMT) improves outcome in patients with stroke and carotid artery dissection (CAD) is unknown.
Methods: This was an international observational study based on prospective nationwide Austrian, German, and Swiss stroke registries. Patients with large vessel occlusion (LVO) due to CAD were compared according to treatment modality (thrombectomy vs BMT including intravenous thrombolysis) and to admission stroke severity NIH Stroke Scale (NIHSS) <6 vs NIHSS ≥6.
Diagnostic Utility of Kappa Free Light Chain Index in Adults With Inaugural Optic Neuritis.
Neurol Neuroimmunol Neuroinflamm
May 2025
Department of Neurology, University Hospital of Marseille, France.
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