AI Article Synopsis

  • The renin-angiotensin-aldosterone system and atrial natriuretic factor play key roles in managing blood flow and changes in the circulatory system.
  • Researchers are focusing on how these systems change during conditions like exogenous hypoxia, which can lead to high-altitude pulmonary hypertension.
  • In their study, the authors measured hormone levels from both vasoconstrictor and vasodilatory systems and compared them to blood flow measurements in native highlanders from the Tien-Shan region.

Article Abstract

Since the renin-angiotensin-aldosterone system and atrial natriuretic factor are directly involved in the regulation of hemodynamics and structural alterations in the circulatory system, the interest of investigators in the observed changes in this system during exogenous hypoxia and the resultant development of high-altitude pulmonary hypertension is quite understandable. The authors measured the plasma levels of hormones from the major vasoconstrictor neurohumoral system and from one vasodilatory system and correlated them with hemodynamic variables in native highlanders of Tien-Shan.

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http://dx.doi.org/10.1177/000331979504600910DOI Listing

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