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Therapeutic Potential of Clove Oil in Mitigating Cadmium-Induced Hepatorenal Toxicity Through Antioxidant, Anti-Inflammatory, and Antiapoptotic Mechanisms.
Pharmaceuticals (Basel)
January 2025
Department of Clinical Pathology, Faculty of Veterinary Medicine, Mansoura University, Mansoura 35516, Egypt.
Unlabelled: Hazardous heavy metals, particularly cadmium (Cd), are widely distributed in the environment and cause oxidative stress in various animal and human organs. Clove oil (CLO), a common aromatic spice, has been used as a traditional medication as it has potent anti-inflammatory, antioxidant, and hepatoprotective properties.
Background/objectives: This study aimed to investigate the antioxidant, antiapoptotic, and anti-inflammatory effects of clove oil (CLO) against hepatorenal toxicity induced by cadmium (Cd).
Investigating the Protective Effects of Luteolin and Gallic Acid from Luffa acutangula L. (Roxb.) amara (Roxb.) C. B. Clarke. Fruit Pericarp Against Alcohol-Induced Liver Toxicity: Extraction, Bioactivity-Guided Fractionation, Molecular Docking, and Dynamics Studies.
J Ethnopharmacol
January 2025
Department of Pharmacognosy, Goa College of Pharmacy, Panaji, Goa, 403 001, India. Electronic address:
Ethnopharmacological Relevance: Luffa acutangula var. amara (Roxb.) C.
View Article and Find Full Text PDFPotential Mechanisms and Effects of Dai Bai Jie Ethanol Extract in Preventing Acute Alcoholic Liver Injury.
Curr Issues Mol Biol
December 2024
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao Di Herbs, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
This study investigated the protective effect of Dai Bai Jie (DBJ) extract against acute alcoholic liver injury (AALI) and elucidated its potential mechanism. The total saponin level in the DBJ extracts was measured using vanillin-chloroform acid colorimetry. To observe the preventive and protective effects of DBJ on AML-12 cells in an ethanol environment, the effective components of DBJ were identified.
View Article and Find Full Text PDFIntegrating immunity, antioxidative status, and gene regulation against nickel and high-temperature stress in fish: selenium nanoparticles for mitigation.
Environ Sci Pollut Res Int
January 2025
ICAR-National Institute of Abiotic Stress Management, Baramati, Pune, 413 115, India.
Fish face health hazards due to high-temperature (T) stress and the toxicity associated with nickel (Ni), both of which can occur in aquatic ecosystems. The accumulation of nickel in fish may pose risks to human health when contaminated fish are consumed. Consequently, the goal of this study was to clarify how selenium nanoparticles (Se-NPs) help Pangasianodon hypophthalmus by reducing the effects of nickel and high-temperature stress.
View Article and Find Full Text PDFAssessing spinel zinc ferrite nanoparticles in aquatic ecosystems: Toxic threat or beneficial detoxifier for aquatic life?
Aquat Toxicol
December 2024
Çanakkale Onsekiz Mart University, School of Graduate Studies, Çanakkale, Turkey. Electronic address:
The effectiveness of magnetic nanoparticles in removing pollutants during water treatment is well established, but their introduction into aquatic ecosystems raises significant toxicity concerns. This study investigates the histological and physiological effects of zinc ferrite magnetic nanoparticles (ZnFeOMNPs) on the Mediterranean mussel (Mytilus galloprovincialis) and examines the impact of concurrent exposure to these nanoparticles and the insecticide thiomethoxam (TMX). Mussels were exposed to nominal concentrations of ZnFeOMNPs (1, 10, 100 mg/L) both individually and with TMX.
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