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Acute Myocardial Infarction Due to Spontaneous Coronary Artery Dissection at 36 Weeks of Pregnancy: A Case Report.
Ann Ital Chir
March 2025
Department of Medical, Surgical, Neurologic, Metabolic and Ageing Sciences, Unit of Colorectal Surgery, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Aim: Acute myocardial infarction in pregnancy (pAMI) is a rare event that is often caused by non-classical factors rather than atherosclerosis. The management of such complications requires a multidisciplinary team, and it is important to bring together the specialties involved to ensure that these teams are coordinated and ready to respond. The management of pAMI poses unique challenges because it requires consideration of both maternal and fetal well-being.
View Article and Find Full Text PDFClinical profiles, treatment adherence, and quality of life in patients with severe mental disorders treated with cyamemazine: A real-world observational study.
Encephale
March 2025
Department of University Psychiatry, Sainte Marguerite University Hospital, Assistance Publique des Hôpitaux de Marseille, Marseille, France; Assistance Publique des Hôpitaux de Marseille, Aix-Marseille University, UR3279: Health Service Research and Quality of Life Center-CEReSS, Marseille, France. Electronic address:
Background: Cyamemazine, a phenothiazine antipsychotic with anxiolytic and sedative properties, is commonly used in the management of severe mental disorders (SMDs) such as schizophrenia, bipolar disorder, and major depressive disorder. Despite its unique pharmacological profile, the impact of cyamemazine on clinical outcomes, treatment adherence, and quality of life (QoL) remains inadequately studied. This study addresses the significant gap in understanding the clinical impact of cyamemazine, a widely used yet under-researched antipsychotic.
View Article and Find Full Text PDFObesity substantially impacts rheumatic and musculoskeletal diseases: time to act.
Ann Rheum Dis
March 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Obesity is a major health problem and risk factor for many chronic health conditions, including rheumatic and musculoskeletal diseases (RMDs). Around 7 in 10 adults with RMD live overweight or with obesity. Obesity not only increases the risk of developing RMDs.
View Article and Find Full Text PDFEffect of testosterone treatment during puberty in boys with Klinefelter syndrome (The TIPY Study): protocol for a nationwide randomised, double-blinded, placebo-controlled study.
BMJ Open
March 2025
Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Introduction: Klinefelter syndrome (KS) is a genetic condition characterised by the presence of an extra X chromosome in males (47,XXY). KS is associated with various phenotypic characteristics in adult life, including infertility, hypogonadism and increased risk of type II diabetes, cardiovascular disease and osteoporosis. Additionally, individuals with KS often experience mental health challenges and functional impairments that significantly impact their quality of life.
View Article and Find Full Text PDFMetabolic Profiles Associate with Mortality and Neurological Outcomes in Out-of-Hospital Cardiac Arrest Patients.
Resuscitation
March 2025
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Background: Out-of-hospital cardiac arrest (OHCA) is associated with high mortality and poor neurological outcome, with significant metabolic changes upon return of spontaneous circulation (ROSC). This study aimed to investigate the association of metabolic derangements with outcomes in patients resuscitated from OHCA.
Methods: Blood samples from 156 consecutive unconscious OHCA patients in the Targeted Temperature Management trial were analyzed at hospital admission.
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