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Morbidity of cancer treatments is well-known. Postradiation sarcomas have been reported though the relative risk is considered to be low. We report a case of osteogenic sarcoma of the face occurring 13 years after irradiation and chemotherapy of bilateral retinoblastoma. In this case chemotherapy, irradiation in the first years of life and retinoblastoma increased the risk of postradiation sarcoma.
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