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Probability of Starting Two-Drug Regimen (2DR) vs. Three-Drug Regimen (3DR) in ART-Naïve and ART-Experienced Person with HIV (PWH) Across the First Wave of COVID-19 Pandemic.
Viruses
November 2024
Centre for Clinical Research, Epidemiology, Modelling and Evaluation (CREME), Institute for Global Health, Univesity College London, London WC1E 6BT, UK.
: This study examined the impact of the COVID-19 lockdown on antiretroviral therapy (ART) prescriptions among persons living with HIV (PWH) in Italy. : Data from the ICONA cohort included ART-naïve individuals who started ART between January 2019 and December 2022, and ART-experienced individuals who started new ART with HIV RNA ≤50 cps/mL from January 2016 to December 2022. The analysis focused on the proportion of PWH starting or switching to dual (2DR) versus triple (3DR) ART regimens.
View Article and Find Full Text PDFT Cell Responses to BA.2.86 and JN.1 SARS-CoV-2 Variants in Elderly Subjects.
Vaccines (Basel)
December 2024
Division of Clinical Immunology-Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, Italy.
Background/objectives: New SARS-CoV-2 variants are continuously emerging, making it essential to assess the efficacy of vaccine-induced immune protection. Limited information is available regarding T cell responses to BA.2.
View Article and Find Full Text PDFTesting and Validation of the Vehicle Front Camera Verification Method Using External Stimulation.
Sensors (Basel)
December 2024
CARISSMA Institute of Electric, Connected, and Secure Mobility (C-ECOS), Technische Hochschule Ingolstadt, Esplanade 10, 85049 Ingolstadt, Germany.
The perception of the vehicle's environment is crucial for automated vehicles. Therefore, environmental sensors' reliability and correct functioning are becoming increasingly important. Current vehicle inspections and self-diagnostics must be adapted to ensure the correct functioning of environmental sensors throughout the vehicle's lifetime.
View Article and Find Full Text PDFPost-Processing Kalman Filter Application for Improving Cooperative Awareness Messages' Position Data Accuracy.
Sensors (Basel)
December 2024
CARISSMA Institute of Electric, Connected and Secure Mobility, Technische Hochschule Ingolstadt, Esplanade 10, 85049 Ingolstadt, Germany.
Cooperative intelligent transportation systems continuously send self-referenced data about their current status in the Cooperative Awareness Message (CAM). Each CAM contains the current position of the vehicle based on GPS accuracy, which can have inaccuracies in the meter range. However, a high accuracy of the position data is crucial for many applications, such as electronic toll collection or the reconstruction of traffic accidents.
View Article and Find Full Text PDFRapid Screening of Etomidate and Its Analogs in Seized e-Liquids Using Thermal Desorption Electrospray Ionization Coupled with Triple Quadrupole Mass Spectrometry.
Toxics
December 2024
Department of Forensic Science, Fujian Police College, Fuzhou 350007, China.
The growing popularity of e-cigarettes has raised significant concerns about the safety and potential abuse of these products. Compounds originally used in the medical field, such as etomidate, metomidate, and isopropoxate, have been illegally added to e-liquids, posing substantial risks to consumer health, and facilitating the misuse of illicit drugs. To address these concerns, this study developed a rapid and efficient method for detecting etomidate, metomidate, and isopropoxate in e-liquids using thermal desorption electrospray ionization coupling triple quadrupole mass spectrometry (TD-ESI/MS/MS).
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