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| http://dx.doi.org/10.1136/sti.71.3.196-a | DOI Listing |
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Sexually transmitted infection rates are increasing in the United States, with significant increases in the rates of syphilis among patients of reproductive age and, subsequently, congenital syphilis. Syphilis screening is recommended in sexually active patients 15 to 44 years of age in communities with high syphilis rates and in all pregnant patients at the time of diagnosis or prenatal intake, in the third trimester, and at delivery. Screening for chlamydia and gonorrhea is currently recommended in asymptomatic, sexually active patients younger than 25 years, as well as in older patients with risk factors.
View Article and Find Full Text PDFPrevalence of and macrolide resistance in rectal and urine samples among men who have sex with men in Sweden.
Sex Transm Infect
October 2024
Department of Laboratory Medicine, Medical Microbiology, Lund University, Lund, Sweden.
Article Synopsis
- The study investigates the prevalence and anatomical distribution of a common rectal infection among men who have sex with men (MSM) in Sweden, focusing on both urine and rectal samples.
- Results reveal that 10.5% of participants had the infection, with a higher detection rate in rectal samples (7.6%) compared to urine samples (3.9%).
- Additionally, the study found a high rate of macrolide resistance mutations, affecting 67.9% of the cases, with rectal infections being predominantly mono infections.
Treponema pallidum genetic diversity and its implications for targeted vaccine development: A cross-sectional study of early syphilis cases in Southwestern Colombia.
PLoS One
July 2024
Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, United States of America.
Background: Venereal syphilis, caused by the spirochete Treponema pallidum subsp. pallidum (TPA), is surging worldwide, underscoring the need for a vaccine with global efficacy. Vaccine development requires an understanding of syphilis epidemiology and clinical presentation as well as genomic characterization of TPA strains circulating within at-risk populations.
View Article and Find Full Text PDFThe Obsolescence of Azithromycin for Syphilis Treatment and the Value of Contrasting Different Types of Evidence.
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Faculdade Israelita de Ciências da Saúde Albert Einstein, Hospital Israelita Albert Einstein, São Paulo, Brazil.
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