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Analysis of the relevant factors for corneal graft rejection in the southern Liaoning region from 2019 to 2023.
Front Med (Lausanne)
January 2025
Dalian Medical University, Dalian, China.
Background: The study aimed to review the etiology of corneal blindness and investigate the relative risk of corneal graft rejection (CGR) in the southern Liaoning region.
Methods: The clinical records of 359 patients (394 eyes) who underwent corneal transplantation at the Department of Keratoconus of the Third People's Hospital of Dalian from January 2019 to December 2023 were retrospectively analyzed. The data included patients' age, gender, occupation, diagnosis, surgical procedure, postoperative immune rejection, and neovascularization.
Eicosapentaenoic acid as an antibiofilm agent disrupts mature biofilms of .
Biofilm
June 2025
Department of Infectious Diseases and Clinical Microbiology, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
The biofilm formation of , a major human fungal pathogen, represents a crucial virulence factor during candidiasis. Eicosapentaenoic acid (EPA), a polyunsaturated fatty acid, has emerged as a potential antibiofilm agent against . .
View Article and Find Full Text PDF(Omphalotaceae, Agaricales), A New Species from Danang, Vietnam.
Mycobiology
December 2024
Faculty of Chemical Technology and Environment, University of Technology and Education, The University of Danang, Danang, Vietnam.
During the collection of macrofungi resources in Son Tra Nature Reserve, Danang, Vietnam, two fungal specimens of the genus , designated as M34295 and M3457, living on dead still-attached branches of L. at an elevation around 360 m above the sea level were recorded. The morphological characteristics of the specimens shared some common characteristics with spp.
View Article and Find Full Text PDFinhibits -induced inflammatory response through targeting HMGB1 in mouse primary peritoneal macrophages.
Heliyon
January 2025
Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Background: () is one of the most common pathogens associated with deep fungal infection, which represents a serious threat to human health. Although high mobility group box 1 (HMGB1) plays a key role in infection, its mechanism is unclear. We aimed to explore the regulation of small-molecule non-coding RNA (miRNA) for HMGB1 in infection.
View Article and Find Full Text PDFExploring the Therapeutic Potential of 1,3-Thiazole: A Decade Overview.
Med Chem
January 2025
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, Marathwada Campus, Jalna-431203, Maharashtra, India.
The escalating prevalence of lifestyle and microbial diseases poses a significant threat to human well-being, necessitating the discovery and development of novel drugs with distinct modes of action. Addressing this challenge involves employing innovative strategies, and one current approach involves utilizing heterocyclic compounds to synthesize hybrid molecules. These hybrids have resulted from the fusion of two or more bioactive heterocyclic moieties into a single molecule.
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