Thirty-two strains of Trichophyton rubrum and 16 strains of Trichophyton mentagrophytes isolated from patients with tinea unguium in various parts of Germany were subjected to a microdilution test with six systemic or topical antimycotic agents. Apart from griseofulvin, there were no species-specific differences between the two species. Terbinafine was the most active antimycotic agent, with a MIC not exceeding 0.05 micrograms/ml.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC162715PMC
http://dx.doi.org/10.1128/AAC.39.5.1206DOI Listing

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