A new sanguinicolid blood fluke, Parasanguinicola vastispina, is described from sea bass Lates calcarifer cultured in Malaysia. It is distinguished by its massive armature and widely spaced genital pores, the female pore being pre-ovarian. P. vastispina inhabits the branchial arteries, dorsal aorta, mesenteric venules and renal artery of its host. No pathological effect was observed in infected fish.

Download full-text PDF

Source
http://dx.doi.org/10.1007/BF00931543DOI Listing

Publication Analysis

Top Keywords

blood fluke
8
fluke parasanguinicola
8
parasanguinicola vastispina
8
sea bass
8
bass lates
8
lates calcarifer
8
cultured malaysia
8
vastispina gen
4
gen nov
4
nov nov
4

Similar Publications

Antibody Responses and the Vaccine Efficacy of Recombinant Glycosyltransferase and Nicastrin Against .

Pathogens

January 2025

National Reference Laboratory for Animal Schistosomiasis, Key Laboratory of Animal Parasitology of Ministry of Agriculture and Rural Affairs, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China.

Schistosomiasis is a neglected tropical disease and the second most common parasitic disease after malaria. While praziquantel remains the primary treatment, concerns about drug resistance highlight the urgent need for new drugs and effective vaccines to achieve sustainable control. Previous proteomic studies from our group revealed that the expression of glycosyltransferase and nicastrin as proteins was higher in single-sex males than mated males, suggesting their critical roles in parasite reproduction and their potential as vaccine candidates.

View Article and Find Full Text PDF

and Evaluation of the Antischistosomal Activity of Polygodial and 9-Deoxymuzigadial Isolated from Branches.

Molecules

January 2025

Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André 09280-560, SP, Brazil.

In the present study, the hexane extract from branches of (Winteraceae) displayed potent activity against parasites (100% mortality of the worms at 200 μg/mL). Bioactivity-guided fractionation afforded, in addition to the previously reported bioactive sesquiterpene 3,6-epidioxy-bisabola-1,10-diene, two chemically related drimane sesquiterpenes-polygodial () and 9-deoxymuzigadial (). The anti- effects for compounds and were determined in vitro, with compound demonstrating significant potency (EC value of 10 μM for both male and female worms), while was inactive.

View Article and Find Full Text PDF

Urinary schistosomiasis is caused by the blood fluke , which is predominantly found in Africa. The freshwater snail is its main intermediate host. The species that make up the group are genetically complex, and their taxonomic status remains controversial.

View Article and Find Full Text PDF

Background: Schistosoma haematobium is the causative pathogen for urogenital schistosomiasis. To achieve progress towards schistosomiasis elimination, there is a critical need for developing highly sensitive and specific tools to monitor transmission in near-elimination settings. Although antibody detection is a promising approach, it is usually unable to discriminate active infections from past ones.

View Article and Find Full Text PDF

Schistosomiasis, caused by Schistosoma worms, is a major neglected tropical disease in Africa, this disease is ranked as second after malaria. Nanotechnology is important for treating schistosomiasis while minimizing chemotherapy side effects. The current investigate aimed to assess the effectiveness of biosynthesized zinc oxide nanoparticles (ZnO NPs), which were used for the first time in an attempt to find alternative treatment for schistosomiasis and synthesized by Origanum majorana, and to compare them with praziquantel (PZQ), the only chemical treatment approved by the World Health Organization.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!