AI Article Synopsis
- Environmental factors like microflora and xenobiotics influence the immune system of both humans and animals.
- Research involving guinea pigs has demonstrated that exposure to coal tar can alter their immunological profile, especially when infected with M. tuberculosis.
- Interestingly, while coal tar exposure can weaken immune response, it may also boost resistance to M. tuberculosis under specific conditions.
Article Abstract
Among most common environmental factors microflora and xenobiotics are capable of changing immunological resistance of human and animal body. Combined action of these factors on the animals has never been studied. Guinea pig experiments showed that M. tuberculosis can significantly change immunogram of the animals exposed for a long time to coal tar. On the one hand, the effect may be negative, but on the other, in certain conditions coal tar enhanced guinea pig's resistance to M. tuberculosis.
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