The authors set forth the indications for operation of selective proximal vagotomy (SPV) combined with closure of perforating pyloroduodenal ulcer and note the peculiarities of SPV technique which they apply. They examined 71 persons in periods of up to 7 years after surgery and 41 patients in periods of up to 16 years. The regional acid-proteolytic activity of the stomach was studied. It was established that SPV lowered the aggressiveness of the gastric contents to a safe level. The digestive activity of the gastric juice did not increase in the studied periods. Operation for suturing of a perforating ulcer in the pyloroduodenal zone in combination with SPV causes a high frequency of stable recovery of patients in the late-term periods. The incidence of recurrent peptic ulcer in follow-up periods of up to 16 years was 5.4%.
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