Two hundred and thirty-six patients had a variety of skin and mucosal wounds sutured with a new rapidly absorbed suture material (irradiated polyglactin 910). No wound complications could be attributed to the material. These included 62 patients with scalp wounds, taking part in a comparative trial with traditional interrupted, monofilament, non-absorbable suturing. No difference in the cosmetic result could be detected three months later. The irradiated polyglactin disappeared from the wound surface spontaneously and suture removal was not normally required. Irradiated polyglactin 910 is suitable for closure of wounds where rapid suture absorption is desirable, particularly for wounds in the scalp, scrotum, and perineum and is an ideal material for mucocutaneous anastomosis at stoma surgery. Loss of suture strength is so rapid that suture removal is unnecessary, eliminating the need for further medical or paramedical care. As absorption is by hydrolysis rather than enzymatic digestion, stitch abscesses are not seen.

Download full-text PDF

Source

Publication Analysis

Top Keywords

irradiated polyglactin
16
polyglactin 910
12
suture removal
8
rapid suture
8
suture
6
irradiated
4
910 synthetic
4
synthetic absorbable
4
absorbable suture
4
suture thirty-six
4

Similar Publications

Background: A common concern among patients following Mohs micrographic surgery (MMS) is scar appearance and residual erythema. However, few studies have quantitatively compared scar erythema between different suture materials.

Objective: To quantify erythema intensity (EI) associated with use of percutaneous nylon, irradiated polyglactin-910 (IPG) and fast-absorbing gut (FG) sutures on facial sites.

View Article and Find Full Text PDF

Objective: Formation of scar on the face after septorhinoplasty may disturb the patient due to cosmetic concerns. One of the main factors affecting scar outcomes is probably the suture material used. The aim of this study was to examine the effect of different suture materials on scar outcomes of alar base in patients undergoing septorhinoplasty.

View Article and Find Full Text PDF

Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen.

ACS Appl Mater Interfaces

November 2021

Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94143, United States.

Article Synopsis
  • Boron neutron capture therapy (BNCT) shows promise as a cancer treatment by targeting prostate-specific membrane antigen (PSMA), which is overexpressed in prostate cancer cells.
  • Researchers developed PSMA-targeted nanoparticles made of PLGA-PEG, loaded with carborane, and attached to a radiometal chelator for more efficient delivery and imaging.
  • Initial tests showed that these nanoparticles accumulated significantly in PSMA-positive tumors compared to PSMA-negative ones, but fast release of carborane limited effective boron delivery to the tumors.
View Article and Find Full Text PDF

Repair of Adult Benign Tracheoesophageal Fistulae With Absorbable Patches: Single-Center Experience.

Ann Thorac Surg

April 2020

Thoracic Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padua, Italy. Electronic address:

Background: This group previously reported on the repair of a wide tracheoesophageal fistula with a bioabsorbable patch. The current study describes a consecutive series of patients operated on using the same technique.

Methods: Data of patients undergoing surgical closure of tracheoesophageal fistula at a single center from 2011 to 2018 were extracted and analyzed.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!