AI Article Synopsis
- The study examined the fructose 6-phosphate/fructose 1,6-bisphosphate substrate cycle using extracts from rat liver, focusing on the dynamics and behavior under continuous substrate supply.
- Various stationary states and damped oscillations were observed in the experiments, aligning with theoretical predictions about the system's behavior.
- The research revealed that altering the adenylate energy charge affects bistability, indicating irreversible changes between different stable states within the cycle.
Article Abstract
The dynamics of the fructose 6-phosphate/fructose 1,6-bisphosphate substrate cycle was investigated in cell-free extracts from rat liver. Under conditions of continuous substrate supply different types of stationary states and damped oscillations were observed experimentally and found to be in qualitative agreement with theoretical predictions. Changing the adenylate energy charge of the substrate supply, bistability was shown to be related to irreversible transitions between functionally different branches of stable stationary states.
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| http://dx.doi.org/10.1515/bchm3.1995.376.1.17 | DOI Listing |
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