Neutralization of feline immunodeficiency virus by polyclonal feline antibody: simultaneous involvement of hypervariable regions 4 and 5 of the surface glycoprotein.
J Virol
Institute of Virology, Erasmus University Rotterdam, The Netherlands.
Published: August 1995
Sites involved in antibody-mediated neutralization of feline immunodeficiency virus were mapped by reciprocal exchange of envelope fragments or amino acids between molecular clones of feline immunodeficiency virus with different susceptibilities to neutralization by a polyclonal cat serum. Combinations of mutations within HV-4 or within HV-4 and HV-5 changed the susceptibility of the viruses to neutralizing antibody.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC189331 | PMC |
| http://dx.doi.org/10.1128/JVI.69.8.5124-5127.1995 | DOI Listing |
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