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Understanding the Interaction of Röntgen Radiation Employed in Computed Tomography/Cone Beam Computed Tomography Investigations of the Oral Cavity by Means of Surface-Enhanced Raman Spectroscopy Analysis of Saliva.
Sensors (Basel)
December 2024
Dental Medicine Faculty, "Iuliu Hatieganu" University of Medicine and Pharmacy, Pasteur 4, 400349 Cluj-Napoca, Romania.
The use of Raman spectroscopy, particularly surface-enhanced Raman spectroscopy (SERS), offers a powerful tool for analyzing biochemical changes in biofluids. This study aims to assess the modifications occurring in saliva collected from patients before and after exposure to cone beam computed tomography (CBCT) and computed tomography (CT) imaging. SERS analysis revealed significantly amplified spectra in post-imaging samples compared to pre-imaging samples, with pronounced intensification of thiocyanate and opiorphin bands, which, together with proteins, dominated the spectra.
View Article and Find Full Text PDFImmediate Nipple Reconstruction in Skin-sparing Mastectomy with A Modified Wise-pattern Design.
Plast Reconstr Surg Glob Open
July 2024
Department of Plastic Surgery, UPMC Williamsport Regional Medical Center, Williamsport, Pa.
This article discusses a novel approach to immediate nipple reconstruction during skin-sparing mastectomy with Wise-pattern design, a common procedure in direct-to-implant breast reconstruction. Traditionally, nipple reconstruction is performed as a second procedure, incurring additional costs and potential complications. This novel technique involves a simple modification to the Wise-pattern flap during the initial mastectomy, allowing for one-step reconstruction.
View Article and Find Full Text PDFDiscriminating Inflammatory Radiation-Related Changes From Early Recurrence in Patients With Glioblastomas: A Preliminary Analysis of 68 Ga-PSMA-11 PET/CT Compared With 18 F-FDOPA PET/CT.
Clin Nucl Med
August 2023
Hospices Civils de Lyon, Lyon.
Purpose Of The Report: Using morphological and functional imaging to discriminate recurrence from postradiation-related modifications in patients with glioblastomas remains challenging. This pilot study aimed to assess the feasibility of using 68 Ga-prostate-specific membrane antigen (PSMA) 11 PET/CT compared with 18 F-FDOPA PET/CT to detect early recurrence.
Methods: Nine patients followed up for glioblastomas who received MRI during 12 months of follow-up were referred for both 68 Ga-PSMA-11 and 18 F-FDOPA PET/CT.
Nanofabrication of Bulk Diffraction Nanogratings via Direct Ultrashort-Pulse Laser Micro-Inscription in Elastomers and Heat-Shrinkable Polymers.
Nanomaterials (Basel)
April 2023
Engineering Physics Faculty, ITMO University, St. Petersburg 197101, Russia.
Optical-range bulk diffraction nanogratings were fabricated via challenging direct inscription by ultrashort (femtosecond, fs) laser pulses inside heat-shrinkable polymers (thermoplastics) and VHB 4905 elastomer. The inscribed bulk material modifications do not emerge on the polymer surface, being visualized inside the materials by 3D-scanning confocal photoluminescence/Raman microspectroscopy and by the multi-micron penetrating 30-keV electron beam in scanning electron microscopy. The laser-inscribed bulk gratings have multi-micron periods in the pre-stretched material after the second laser inscription step, with their periods continuously reduced down to 350 nm on the third fabrication step, using thermal shrinkage for thermoplastics and elastic properties for elastomers.
View Article and Find Full Text PDFEvaluation of Standard Response Assessment in Neuro-Oncology, Modified Response Assessment in Neuro-Oncology, and Immunotherapy Response Assessment in Neuro-Oncology in Newly Diagnosed and Recurrent Glioblastoma.
J Clin Oncol
June 2023
Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA.
Article Synopsis
- * Analysis included 526 patients with newly diagnosed GBM and 580 with recurrent GBM, revealing similar correlations in progression-free survival (PFS) and overall survival (OS) between RANO and mRANO.
- * Findings indicate that confirmation scans within 12 weeks post-radiotherapy improve assessment accuracy, while the iRANO criteria did not provide additional benefits over RANO and mRANO.
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