The incidence and the titer of rubella virus antibodies in sera of 936 girls (average age 21 year) from 5 medical school were examined. The antibodies were determined in HI test (Rubenosticon, Organon Teknika). Serum samples were collected in the period of I.1990-IX.1994, and the antibody titer > or = 1:16 was accepted as positive. In 80.3 percent of the examined girls antibodies were found. The mean titer was 1:34.5. Out of 184 seronegative girls, 95 were immunized with Rudivax vaccine. Seroconversion occurred in all, but one person, the mean titer of antibodies was 1:54.6. In 2 vaccinated girls only mild side-effect after immunization occurred.
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