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Cell-free DNA release following psychosocial and physical stress in women and men.
Transl Psychiatry
January 2025
Department of Genetic Psychology, Faculty of Psychology, Ruhr-University Bochum, Universitätsstraße 150, Bochum, Germany.
Cell-free DNA (cfDNA) is continuously shed by all cells in the body, but the regulation of this process and its physiological functions are still largely unknown. Previous research has demonstrated that both nuclear (cf-nDNA) and mitochondrial (cf-mtDNA) cfDNA levels increase in plasma in response to acute psychosocial and physical stress in males. This study further investigated these findings by testing 31 female participants (16 using oral hormonal contraception and 15 not using oral hormonal contraception), and the results were subsequently compared with those of 16 male participants.
View Article and Find Full Text PDFCell-free systems: A synthetic biology tool for rapid prototyping in metabolic engineering.
Biotechnol Adv
January 2025
Division of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk 37673, Republic of Korea; Department of Chemical Engineering, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-Gu, Pohang, Gyeongbuk 37673, Republic of Korea. Electronic address:
Microbial cell factories provide sustainable alternatives to petroleum-based chemical production using cost-effective substrates. A deep understanding of their metabolism is essential to harness their potential along with continuous efforts to improve productivity and yield. However, the construction and evaluation of numerous genetic variants are time-consuming and labor-intensive.
View Article and Find Full Text PDFHidradenitis suppurativa.
Lancet
January 2025
Faculty of Medicine, Wroclaw University of Science and Technology, Wrocław, Poland.
Hidradenitis suppurativa is a chronic inflammatory disease characterised by painful, deep-seated nodules, abscesses, and draining tunnels in the skin of axillary, inguinal, genitoanal, or inframammary areas. In recent years, the body of knowledge in hidradenitis suppurativa has advanced greatly. This disorder typically starts in the second or third decade of life.
View Article and Find Full Text PDFBoron-dependent autoinducer-2-mediated quorum sensing stimulates the Cr(VI) reduction of Leucobacter chromiireducens CD49.
J Environ Manage
January 2025
Department of Occupational and Environmental Health, Xiangya School of Public Health, Central South University, Changsha, China. Electronic address:
Traditionally, abiotic factors such as pH, temperature, and initial Cr(VI) concentration have been undoubtedly recognized as the external driving forces that dramatically affect the microbial-mediated remediation of Cr(VI) pollutants. However, concentrating on whether and how the biological behaviors and metabolic activities drive the microbial-mediated Cr(VI) detoxification is a study-worthy but little-known issue. In this study, Leucobacter chromiireducens CD49 isolated from heavy-metal-contaminated soil was identified to tolerate 8000.
View Article and Find Full Text PDFEffect of glyphosate on renal function: A study integrating epidemiological and experimental evidence.
Ecotoxicol Environ Saf
January 2025
Department of Pediatrics, The Third Xiangya Hospital of Central South University, Changsha 410013, China. Electronic address:
Glyphosate, a widely used herbicide globally, has prompted concerns regarding its potential health impacts. This study aimed to explore the link between glyphosate exposure and renal function by combining NHANES, a zebrafish model, and metabolomics. A cross-sectional analysis of 2013-2014 NHANES data investigated the relationship between glyphosate exposure and renal function [albumin-to-creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR)].
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