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Effects of household cleaning products on the lungs: an update.
Expert Rev Respir Med
March 2025
Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Équipe d'Épidémiologie Respiratoire Intégrative, CESP, Villejuif, France.
Introduction: Household disinfectants and cleaning products (HDCPs), which involve a complex mixture of chemical ingredients, are commonly used in homes. HDCPs significantly contribute to chemical exposure in the indoor environment by releasing particles and volatile organic compounds while being used, potentially harming the respiratory health of those exposed.
Areas Covered: We provide an overview of scientific literature, especially from the last five years, regarding the (i) effects of using of HDCPs on adults' respiratory health; (ii) associations between prenatal or childhood exposure to HDCPs and children respiratory health.
Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.
Front Bioeng Biotechnol
February 2025
Department of Biomedical Engineering and Chemical Engineering, University of Texas at San Antonio, San Antonio, TX, United States.
Background: Inhalation injuries, caused by exposure to extreme heat and chemical irritants, lead to complications with speaking, swallowing, and breathing. This study investigates the effects of thermal injury and endotracheal tube (ETT) placement on the airway microbiome and inflammatory response. A secondary aim is to assess the impact of localized dexamethasone delivery via a drug-eluting ETT to reduce laryngeal scarring.
View Article and Find Full Text PDFOccupational exposure and chronic bronchitis in a sample of the general population in Telemark, Norway: a two-phased cross-sectional study.
Occup Environ Med
March 2025
Division of Occupational, Environmental and Climate Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Objectives: We aimed to estimate the prevalence of chronic bronchitis (CB), examine its association with occupational exposure to irritants assessed by self-reporting or the Nordic job exposure matrix (N-JEM) stratified by smoking status and estimate the population-attributable fraction (PAF) of CB from occupational exposure.
Methods: A two-phased, cross-sectional design was used to analyse a random sample collected in 2013 and 2018 of the population aged 16-55 years in Telemark County, Norway. CB was defined as cough and sputum production for ≥3 months over 2 consecutive years.
Climate Change and Allergens: Current and Future Impacts.
J Allergy Clin Immunol Pract
March 2025
Department of Pediatrics, College of Medicine, Hanyang University, Seoul, Korea. Electronic address:
Climate change will continue to impact allergic diseases in direct and indirect ways. Rising global temperatures are contributing to increased duration of pollen seasons, altered aeroallergen production and potency of allergens, and changes in the geographic distribution of allergenic plants that drive increased human exposure to aeroallergens and increased allergic disease morbidity. Climate change is inextricably linked with air pollution, the latter of which was shown to act as an adjuvant for allergic inflammatory processes promoting allergic sensitization.
View Article and Find Full Text PDFA Novel Ammonium Carboxylate Salt of Undecylenic Acid for the Topical Treatment of Gram-Positive and Antibiotic-Resistant Skin Infections.
Exp Dermatol
March 2025
Wintermute Biomedical Inc., Missoula, Montana, USA.
Uncomplicated topical skin infections like impetigo, caused by gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes, are a common global health issue, particularly affecting children. With increasing antimicrobial resistance, conventional treatments such as mupirocin are becoming ineffective, highlighting the necessity for new antimicrobial development. Fatty acids have long shown potential as novel antimicrobials, but their development has been limited by solubility and efficacy concerns in topical applications.
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