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Background: Understanding the fundamental differences between the human and pre-human brain is a prerequisite for designing meaningful models and therapies for AD. Expressed CHRFAM7A, a human restricted gene with carrier frequency of 75% in the human population predicts profound translational significance.
Method: The physiological role of CHRFAM7A in human brain is explored using multiomics approach on 600 post mortem human brain tissue samples (ROSMAP).
Dementia Care Research and Psychosocial Factors.
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University of British Columbia, Vancouver, BC, Canada.
Background: Co-creation methods are increasingly being used in the research and development of technologies that support older adults living with dementia and their care partners to live well. Use of collaborative methods to engage with the dementia community helps to ensure that research processes and end solutions are sensitively designed, reflective of needs and values, and responsive to priorities. Engagement also has proximal benefits for older adults: Being involved in purposeful activity has been shown to positively impact health and wellbeing outcomes.
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Fleni, Buenos Aires, CABA, Argentina.
Background: LatAm-FINGERS is the first non-pharmacological multicenter randomized clinical trial aimed at preventing cognitive impairment in Latin America. It encompasses twelve countries that collectively represent 45% of the territory in the Americas. Its objective is to reach populations that, despite sharing commonalities such as language, are culturally and economically diverse.
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University of New Hampshire, Durham, NH, USA.
Background: There is a growing number of residents living with dementia (RLWD) in long-term care (LTC) settings, but dementia care access and quality are more limited in communities with fewer health resources and these limitations are exacerbated by current dementia care workforce shortages. Low-resource LTC settings, including poorer urban and rural settings, serve older adults who are at high risk for health inequities in dementia care. These settings can experience barriers in providing quality dementia care due to their limited ability to capture pertinent information about residents' needs and preferences and ensuring that information is known by dementia care staff.
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Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.
Background: Caregivers of people with dementia (PwD) often experience the burden of caregiving and depressive symptoms that may be associated. PwD who experience a higher occurrence of neuropsychiatric symptoms often cause a greater burden on their caregivers due to the difficulty in managing these symptoms. Caregivers may transfer their feelings of frustration and exhaustion with caregiving through the way they communicate with the PwD.
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