Post-traumatic stress disorder (PTSD) is a psychobiological concept. Distressing events outside the range of usual human experience produce several somatovegetative and especially several psychic disturbances. The psychoneuroendocrine mechanisms of PTSD concern the impact of cognitive factors, a disorder of arousal and alterations of the central sympathoadrenal system and of the noradrenergic mediation. The authors exhibited the influence of stressful events (uprising of December 1989 in Romania) on the intestinal and noncoronary cardiovascular complains and analysed five cases of PTSD, treated in the last three years.

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