Intraperitoneal administration of 5-HT2-receptor blocking agent ciproheptadine abolished the protective effect on stress-induced damage of gastric mucosa in male mice, while propranolol depresses this protective effect. Propranolol prevented a damaging effect of serotonine on gastric mucosa. Consequences of emotional stress on gastric mucosa seem to be realised through different types of serotoninergic receptors.
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