The effects of Codonopsis pilosula oral liquor (CPOL) on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI) in the plasma of 25 patients of coronary heart disease with blood stasis were studied. It has been shown that those patients had a significant decrease in t-PA activity (P < 0.01) compared to healthy subjects. After 4 weeks of CPOL therapy, platelet aggregation significantly decreased (P < 0.05), there was no significant difference in t-PA and PAI. From the results shown above, it suggested that one of the effects of CPOL in influencing blood coagulation was its inhibition on platelet aggregation, but not through the elevating of fibrinolytic activity.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Immunoregulatory Effects of Polysaccharide Modified Selenium Nanoparticles on H22 Tumor-Bearing Mice.
Foods
December 2024
Yantai Key Laboratory of Characteristic Agricultural Bioresource Conservation & Germplasm Innovative Utilization, School of Life Sciences, Yantai University, Yantai 264005, China.
polysaccharide (CPP) and rare element selenium (Se) have been proved to exert various biological activities, and our previous study demonstrated that selenium nanoparticles modified with CPP (CPP-SeNPs) possessed significantly enhanced tumor cytotoxicity in vitro. This study aimed to investigated the inhibitory effects of CPP-SeNPs complex on H22 solid tumors via immune enhancement. In this study, the H22 tumor-bearing mice model was constructed, and the potential mechanisms of CPP-SeNPs antitumor effects were further explored by evaluating cytokines expression levels, immune cells activities and tumor cells apoptotic indicators in each group.
View Article and Find Full Text PDFTranscription factors CpSPL5 and CpSPL8 negatively regulate salt tolerance in Codonopsis pilosula by inhibiting SOS pathway.
Plant J
December 2024
Key Laboratory of the Ministry of Education for Medicinal Resources and Natural Pharmaceutical Chemistry, National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China, Shaanxi Normal University, Xi'an, China.
Environmental stresses such as salt and drought severely affect plant growth and development. SQUAMOSA-promoter binding protein-like (SPL) transcription factors (TFs) play critical roles in the regulation of diverse processes; however, reports describing the SPL regulation of plant responses to abiotic stress are relatively few. In this study, two stress-responsive TFs from Codonopsis pilosula (CpSPL5 and CpSPL8) are reported, which confer salt stress sensitivity.
View Article and Find Full Text PDFFermented residue improved milk performance of lactating donkeys by enhancing antioxidant capacity and regulating metabolism.
Front Vet Sci
November 2024
College of Agriculture and Biology, Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, Liaocheng University, Liaocheng, China.
The fermented residue (FCPR) has a promoting effect on animal health, but it has not been studied in livestock feed. This study investigated the effects of FCPR addition on the milk performance, milk metabolites, and blood biochemical parameters and metabolites of lactating donkeys. Twelve healthy multiparous lactating Dezhou donkeys were randomly divided into two groups (with 6 donkeys in each group): control group (without FCPR, C) and FCPR group (200 g of FCPR per head per day, FF).
View Article and Find Full Text PDFResearch status and future focus on : A bibliometric analysis of past and present studies.
Heliyon
November 2024
Collaborative Innovation Center for Comprehensive Development of Biological Resources in Qinba Mountain Area of Southern Shaanxi, Qinba Provincial Key Laboratory of Biological Resources and Ecological Environment, Shaanxi Province Key Laboratory of Bio Resources, College of Biological Science and Engineering, Shaanxi University of Technology, Hanzhong, China.
Background: is a traditional herb widely used in Asian countries. As regulatory institutions increasingly acknowledge its medicinal and food-related characteristics, the attention from scholars is expected to increase rapidly. However, an overview and reports on research focus on this promising herb are currently lacking.
View Article and Find Full Text PDFMetabolomic Analysis of Specific Metabolites in Soil Under Different Stubble Conditions.
Molecules
November 2024
State Key Laboratory of Aridland Crop Science, Agronomy College, Gansu Agricultural University, Lanzhou 730070, China.
To investigate the soil-specific metabolites of under different stubble management practices, this study analyzed differentially abundant metabolites in the rhizosphere soils of rotational (DS) and continuous (LS) cropping systems via liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based metabolomic approaches. The results revealed that 66 metabolites, including amino acids and their derivatives, nucleic acids, alcohols, organic acids, amines, fatty acids, purines, and sugars, were significantly different ( < 0.05) between the DS and LS groups.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!