Dissection of the human poly(ADP-ribose) polymerase (PARP) molecule in terms of its structure-function relationship has proved to be an essential step towards understanding the biological role of poly(ADP-ribosylation) as a cellular response to DNA damage in eukaryotes. Current approaches aimed at elucidating the implication of this multifunctional enzyme in the maintenance of the genomic integrity will be presented.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0300-9084(96)88160-0 | DOI Listing |
Publication Analysis
Top Keywords
polyadp-ribose polymerase
8
structure-function relationship
8
polymerase structure-function
4
relationship dissection
4
dissection human
4
human polyadp-ribose
4
polymerase parp
4
parp molecule
4
molecule terms
4
terms structure-function
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!