Hedonic deficit in chronic schizophrenia.

Forty-two chronic schizophrenic patients were evaluated for extent of hedonic deficit and compared with a demographically matched sample of normals. Schizophrenics rated themselves as experiencing significantly less pleasure on four of ten pleasure factors. When the schizophrenic sample was divided into depressed and non-depressed subgroups, the depressed subgroup was found to account for these differences in pleasure between schizophrenics and normals. Psychobiological implications of these results are discussed.